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Unveiling the Future of
Non-Targeted Screening
Welcome to LECO, where innovation meets precision, even for unknown sample testing. Our cutting-edge GC×GC and HRT/MMS technologies redefine non-targeted screening, empowering laboratories across all industries. Explore the limitless possibilities as we revolutionise screening techniques for enhanced quality and confidence in results.
"Join us in navigating non-targeted frontiers, where possibilities are limitless, and results are unparalleled.
Choose LECO –
your partner in revolutionising
non-targeted screening."
Explore Our Products
Dive into our comprehensive range of products designed to meet the unique challenges of non-targeted screening. From food safety and environmental analysis to pharmaceutical and petrochemical applications, LECO's advanced instrumentation offers unparalleled insights and efficiencies. Elevate your laboratory's capabilities with our state-of-the-art solutions.
Find further details about LECO's PEGASUS® instruments on our separation science analysis compendium page.
Watch the Webinar - 5 aprileth, 2024
Join us on 5 aprileth for an immersive webinar experience. Discover the latest advancements in non-targeted screening technologies, practical applications, and case studies that showcase the power of LECO's GC×GC and HRT systems. Don't miss this opportunity to stay ahead in the rapidly evolving landscape of substance analysis.
LECO NTS Sympoium 2024
Join us in Manchester, Berlin or Nice and take your chance to be part of this transformative experience.
- settembre 17 – 18, 2024 Alderley Park, Manchester, UK
- ottobre 28 – 30, 2024 Berlin EATC, GER
- novembre 19 – 21, 2024 Nice Université Côte d'Azur, Nice, FR
Download Brochures
Get in-depth insights into our product offerings through our informative brochures. Understand how LECO's technology addresses the evolving challenges of identifying emerging contaminants. Equip your laboratory with robust, versatile, and cost-effective non-target screening workflows.
Access Application Notes
Delve into real-world scenarios with our NTS application notes. Gain practical knowledge on how LECO's GC×GC and HRT/MMS technologies provide unmatched results in substance screening. From improved accuracy to increased efficiency, our application notes demonstrate the impact of choosing LECO as your non-targeted screening partner.
In the following, you are going to find a content compendium. You can download them here with a click.
- Comprehensive Evaluation of Scotch Whisky Aroma Profiles Using SPME-GC×GC-TOFMS
- Discovery of Environmental Pollutants at an Electronic Waste Recycling Facility by PEGASUS® GC-HRT+ 4D
- Expand Your PFAS Analysis. Screen for Targets and Identify Unknowns Simultaneously
- Analisi forensi del petrolio: Identificazione dei biomarcatori nel petrolio greggio
- Analysis of Heavy Fuel Oil Using Multi-Mode Ionization
- Characterization of Extractables from Common Pharmaceutical Packaging Materials with GC×GC and HR-TOFMS
- Workflow for the Assessment of Key Aroma Compounds of Pumpernickel Bread Variations
- The Development of Untargeted Metabolite Profiling Methodology for the Analysis of Type-2 Diabetes Patient Plasma
Why Choose LECO?
Innovative Technologies
GC×GC and HRT/MMS technologies redefine non-targeted screening, offering unmatched precision and efficiency.
Comprehensive Solutions
Address the evolving challenges of substance screening across diverse markets, from identifying emerging contaminants to ensuring food safety.
Cost-Effective Workflows
Enhance your efficiency without compromising on quality. LECO provides cost-effective solutions without sacrificing performance.
Market
Leadership
Position your laboratory at the forefront of non-targeted screening with LECO's capabilities.
If you want to learn more about our products and solutions for non-target screening, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
I use LECO PEGASUS® BT 4D to separate, identify and quantify secondary metabolites of various organisms. The advantages of the GC×GC system in separation of multi-component mixtures allow us to separate and identify a huge number of compounds in every samples. The ability to separate and quantify low levels of target analytes in mixtures simultaneously with the major components presented at a high level of concentration and to separate coeluted compounds is a great advantage of two-dimensional GC in comparison with one-dimensional GC. The user-friendly ChromaTOF software and excellent technical support make LECO a reliable partner for researcher. Since we started working on this equipment, our results have become more accurate and comprehensive, and our research has reached a new level.
In our lab, the GC×GC-MS device installed by LECO has been a game-changer for metabolic profiling, especially in our multiomics study exploring the intricacies of obesity in young adults. Its sensitivity has been crucial in identifying and quantifying metabolites, even at low concentrations, essential for uncovering subtle changes in the metabolome. Our experience with PEGASUS® BT 4D device has been exceptionally positive, significantly due to the exceptional support of the service team, ensuring the smooth operation and optimal performance of our instrument.
We started using the LECO PEGASUS® BT GC-TOF mainly for target analysis of aliphatic hydrocarbons on environmental matrices; over time we had the need to develop a method for the qualitative characterization of hop leaves samples for a research project, the ChromaTOF® deconvolution software allowed the identification of several compounds, in particular different terpenes. The Pegasus BT GC-TOF thus proved to be an excellent system, easy to use, with high sensitivity and reproducibility, able to perform both non target and target analysis.
I started working with the PEGASUS GC-HRT+ 4D back in my student years. As a novice researcher, with no experience working with similar devices and no training, it was not easy at first. However, after years of working with this instrument and when compared with other sophisticated equipment in the field of gas chromatography - high-resolution mass spectrometry, I can confidently say that the ChromaTOF is the most user-friendly software of all those available now. Such a variety of functions, as well as very clear, convenient, and fast operation, combined with high-tech equipment, allows to get very decent results.
Over the past 5 years of using the Pegasus GC-HRT+ 4D, we have been able to conduct many various environmental studies, identifying trace amounts of substances in the cleanest Arctic environmental objects. At the same time, such a powerful combination of two-dimensional gas chromatography with time-of-flight mass spectrometry made it possible to analyze complex matrices, namely peat combustion products, herbal and tobacco cigarette smoke, petroleum and much more.
It is worth noting the work of the support service, which helped us very quickly and efficiently. I would like to thank the engineers for their work, who were on call almost 24/7. There are still many projects and tasks ahead that will undoubtedly be solved with the help of the Pegasus GC-HRT+ 4D.
Unveiling the Future of
Non-Targeted Screening
Welcome to LECO, where innovation meets precision, even for unknown sample testing. Our cutting-edge GC×GC and HRT/MMS technologies redefine non-targeted screening, empowering laboratories across all industries. Explore the limitless possibilities as we revolutionise screening techniques for enhanced quality and confidence in results.
"Join us in navigating non-targeted frontiers, where possibilities are limitless, and results are unparalleled.
Choose LECO –
your partner in revolutionising
non-targeted screening."
Explore Our Products
Dive into our comprehensive range of products designed to meet the unique challenges of non-targeted screening. From food safety and environmental analysis to pharmaceutical and petrochemical applications, LECO's advanced instrumentation offers unparalleled insights and efficiencies. Elevate your laboratory's capabilities with our state-of-the-art solutions.
Find further details about LECO's PEGASUS® instruments on our separation science analysis compendium page.
Watch the Webinar - 5 aprileth, 2024
Join us on 5 aprileth for an immersive webinar experience. Discover the latest advancements in non-targeted screening technologies, practical applications, and case studies that showcase the power of LECO's GC×GC and HRT systems. Don't miss this opportunity to stay ahead in the rapidly evolving landscape of substance analysis.
LECO NTS Sympoium 2024
Join us in Manchester, Berlin or Nice and take your chance to be part of this transformative experience.
- settembre 17 – 18, 2024 Alderley Park, Manchester, UK
- ottobre 28 – 30, 2024 Berlin EATC, GER
- novembre 19 – 21, 2024 Nice Université Côte d'Azur, Nice, FR
Download Brochures
Get in-depth insights into our product offerings through our informative brochures. Understand how LECO's technology addresses the evolving challenges of identifying emerging contaminants. Equip your laboratory with robust, versatile, and cost-effective non-target screening workflows.
Access Application Notes
Delve into real-world scenarios with our NTS application notes. Gain practical knowledge on how LECO's GC×GC and HRT/MMS technologies provide unmatched results in substance screening. From improved accuracy to increased efficiency, our application notes demonstrate the impact of choosing LECO as your non-targeted screening partner.
In the following, you are going to find a content compendium. We kindly ask you to submit our form. Afterwards you‘ll get access to all the files.
- Comprehensive Evaluation of Scotch Whisky Aroma Profiles Using SPME-GC×GC-TOFMS
- Discovery of Environmental Pollutants at an Electronic Waste Recycling Facility by PEGASUS® GC-HRT+ 4D
- Expand Your PFAS Analysis. Screen for Targets and Identify Unknowns Simultaneously
- Analisi forensi del petrolio: Identificazione dei biomarcatori nel petrolio greggio
- Analysis of Heavy Fuel Oil Using Multi-Mode Ionization
- Characterization of Extractables from Common Pharmaceutical Packaging Materials with GC×GC and HR-TOFMS
- Workflow for the Assessment of Key Aroma Compounds of Pumpernickel Bread Variations
- The Development of Untargeted Metabolite Profiling Methodology for the Analysis of Type-2 Diabetes Patient Plasma
Why Choose LECO?
Innovative Technologies
GC×GC and HRT/MMS technologies redefine non-targeted screening, offering unmatched precision and efficiency.
Comprehensive Solutions
Address the evolving challenges of substance screening across diverse markets, from identifying emerging contaminants to ensuring food safety.
Cost-Effective Workflows
Enhance your efficiency without compromising on quality. LECO provides cost-effective solutions without sacrificing performance.
Market
Leadership
Position your laboratory at the forefront of non-targeted screening with LECO's capabilities.
If you want to learn more about our products and solutions for non-target screening, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
Explore the Fascinating World of Separation Science
The very first GC-MS was a GC-TOFMS which was built in 1947. The information it provided was much too large to record, and it was not until the mid-1990s when LECO introduced the first fast GC-TOFMS, that GC-TOFMS became a useable tool for researchers and analysts. Followed a few years later by LECO’s introduction of the first GC×GC-TOFMS.
Today, LECO’s Separation Science products are recognised across the globe as leading advanced technology innovations in TOFMS Mass Spectrometry and Comprehensive two-dimensional Chromatography.
PEGASUS® BT GC-TOFMS
GC Time-Of-Flight Mass Spectrometer
Today‘s laboratories are being asked for more everyday – more samples run, more data acquired, more chemical information processed, and more results achieved – all in less time, for less money. ...
The Pegasus BT allows you to achieve all you need from a single sample run, while powerful and user-friendly ChromaTOF® software processes your data and removes the guesswork involved with analyte identification, quantitation, and reporting. The Pegasus BT gives users more uptime, better data, and an increase in overall productivity and efficiency.
Uno spettrometro di massa a tempo di volo (TOFMS) è l'ideale per scoprire nuovi composti nel campione, quantificare i composti target in campioni complessi e aumentare la produttività con la cromatografia rapida.
► Download the free whitepaper and brochure
PEGASUS® BT 4D GC×GC-TOFMS
GC×GC Time-Of-Flight Mass Spectrometer
The Pegasus BT 4D offers enhanced sensitivity by coupling our benchtop Pegasus BT with a high-performance GC×GC modulation system. This combination gives the Pegasus BT 4D the ability to interrogate challenging samples ...
... where the best sensitivity is needed. Le funzionalità software e hardware uniche e potenti semplificano la quantificazione, permettono inoltre che GCxGC sia incredibilmente facile da utilizzare e da comprendere. Our thermal modulation system, the QuadJet™, is recognised as the gold standard in GC×GC modulation, providing the highest sensitivity available on the market - ideal for analysing the most complex samples.
One of the main advantages of LECO’s GC×GC-TOFMS is its ability to provide vastly improved peak capacity and resolution than traditional GC-MS systems. It also offers comprehensive information about the sample by separating compounds based on two different properties (volatility and polarity). Combining GC×GC with TOFMS is an ultimate solution for the analysis of complex samples.
► Download the free brochure
PEGASUS® GC-HRT+
High Resolution Time-Of-Flight Mass Spectrometer
Now with even more sensitivity than ever before, the Pegasus GC-HRT+ is the perfect tool for meeting the challenges of today’s highly complex analytical demands. ...
This high-resolution mass spectrometer features industry leading mass accuracy, full mass range acquisition with exceptional speed, full mass range acquisition with exceptional speed, isotopic abundance and mass resolution, all available in a single injection.
Folded Flight Path® (FFP®) technology and a novel data acquisition system enables simultaneous resolutions of over 50,000 FWHM, mass accuracies less than 1 ppm, and acquisition rates up to 200 spectra/second, without the need to adjust tuning or parameters. Thus, facilitating rich analyte finding and high-confidence analyte identification.
► Download the free brochure
PEGASUS® GC-HRT+ 4D
HR GC×GC Time-Of-Flight Mass Spectrometer
The Pegasus GC-HRT+ 4D combines the highest performance GC×GC and TOFMS tools on the market with High Resolution Deconvolution® (HRD®). Ideal for the most complex samples, ...
... users are able to find more analytes than ever before and confidently identify unknown components.
The Pegasus GC-HRT+ 4D takes advantage of four dimensions of separation and resolution:
- 1st dimension chromatographic resolution
- 2nd dimension chromatographic resolution
- High mass resolution and exceptional mass accuracy
- High Resolution Deconvolution (HRD) from the leaders in deconvolution
ChromaTOF brand software, designed specifically for HRT+ instrumentation and GC×GC support, adds advanced qualitative and quantitative capabilities to an all-in-one user-friendly data system.
► Download the free brochure
Examples of LECO Separation Science Applications
Petrolio
Comprehensive Two-Dimensional Gas Chromatography (GC×GC) has proven to be an extremely valuable analytical technique for the petroleum industry due to its ability to substantially increase the chromatographic peak capacity beyond that of traditional single-dimension gas chromatography. Pairing GC×GC with Time-of Flight Mass Spectrometry (TOFMS) provides unsurpassed characterization capabilities due to the separation power of GC×GC and the ability of TOFMS to provide rich data.
Food Testing
The characterization and safety testing of food and food constitutions can be extremely challenging depending on the complexity and the matrix. The LECO GC×GC TOFMS technology provides a highly powerful separation and remarkable identification allowing for improved workflows. More insights thanks to the advanced technology in combination with LECO’s ChromaTOF® brand software deconvolution algorithm and advanced data analysis tool will improve your Food Quality & Safety Testing and Food R&D. Here we demonstrate the aroma analsyis of two types of coffee and coffee packaging and filter leachates.
Perfume and Cosmetics
LECO‘s GC×GC-TOFMS is a valuable asset in the production of cosmetics and perfumes that align with Islamic principles. It can be used to identify the ingredients and detect any prohibited substances such as alcohol or non-halal animal-derived ingredients.
Analisi ambientale
Microplastics are an emerging pollutant which are widely distributed in the environment. Understanding the impact of their growing prevalence on the environment and human health is an important field of research. LECO‘s GC×GC-TOFMS can be used to monitor environmental pollution and air and water quality thus aiding to enforce regulations and ensure the preservation of our environment.
Metabolomica
LECO’s key advantage is the ability to identify and discover more metabolites than other similar technologies. La nostra velocità di acquisizione della scansione completa non ha rivali e, se combinata con la potenza dell'algoritmo di deconvoluzione del marchio software ChromaTOF®, consente una caratterizzazione dei sistemi biologici allo studio. La nostra strumentazione è stata validata dai ricercatori più esigenti del settore.
Extractables and Leachables
The characterization of extractable and leachable components from a wide range of materials is an important area of research. Information about extractable and leachable components from packaging and delivery devices for pharmaceutical products is a particular area of growing interest. Analytical testing results on this topic are part of many regulatory submission requirements to the FDA. ...
USP 1663 provides guidance on extractables testing and a variety of analytical approaches can meet compliance. High resolution MS is often considered necessary for identification of unknowns, and sample complexity and low-level detection continue to challenge these analyses. Here, we demonstrate a workflow that uses comprehensive two-dimensional gas chromatography (GC×GC) with HR-TOFMS to help address these challenges.
► App Note | Characterizing Extractables by GC×GC & HR-TOFMS
FAQ – Separation Science
Answer:
Gas chromatography separates components in a mixture by utilizing a thin silica tube coated with a stationary phase. The components, carried by a gas (the mobile phase), move at different speeds based on their affinities for the stationary phase. This differential migration leads to the separation of the components, allowing for their individual analysis and identification.
Alternative response:
- Gas chromatography is a technique for separating a mixture of volatile analytes
- The analytes are transported by a mobile phase (the carrier gas)
- Become distributed between the mobile phase and a stationary phase
- The Stationary Phase is attached to the inside of a very fine column
- Phases are typically characterised by their polarity
- A polar analyte will be retained by polar column for longer than a non-polar analyte
- and vica versa
Answer:
LECO uses Agilent 8890 chromatography. The gas chromatograph includes the following features:
- Compatibility and perfect integration with the mass spectrometer
- Automatic regulation of gas flows
- Agilent supported inlets: Split/Splitless (SSL), Multimode (MMI), Programmable temperature Vaporizer (PTV) etc.
- Programmable oven, up to 450 °C
- Chromatograph compatible with Fast-GC
- The GC is completely controlled by and integrated into LECO’s ChromaTOF software
Answer:
The LECO mass spectrometer is connected to the GC via a heated transfer line. The LECO GC-TOF allows you to have a 'full range' acquisition, without compromise, then a targeted and/or non-targeted data exploitation depending on what you want to do.
It consists of an EI (Electronic Impact) source, a 70 cm flight tube, a reflectron and a detector. Vacuum is provided by an internal turbomolecular pump connected to an external secondary pump.
Answer:
The mass range of the Pegasus BT is from 10 to 1500 m/z. All masses are collected all the time, unlike quadrupole instruments that collect a single mass at a time (quadrupole scanning mode is single ion monitoring, SIM, quickly scanning across the mass range).
Answer:
GC×GC-TOFMS can detect discrepancies in the composition of food products, helping to expose fraudulent claims of Halal certification and ensure consumer confidence in authentic Halal products.
Answer:
By examining the chemical composition of inks and pigments, GC×GC-TOFMS provides insights into the materials used in Islamic calligraphy and manuscripts, aiding in their preservation and authentication. An example of similar work can be read in this publication on analysing the paints used by Leonardo Da Vinci.
Answer:
LECO’s GC×GC-TOFMS system utilizes two columns with different separation mechanisms, providing enhanced chromatographic resolution for the analysis of complex mixtures. In one dimension the analytes are separated by polarity, or according to boiling point. An additional dimension separates according to an alternative property, of which there are many. This results in a 3D image – the two dimensions of separation and the abundance of the analytes in the third dimension.
Answer:
LECO's StayClean® ion source originates in the requirement for a fast source to match the speed of the TOFMS. Accomplished by reducing ion to ion interactions, such as with the walls of the source. The source was thus designed without walls – so there is nothing to clean. Massively reduced downtimes, especially for complex matrices and more reproducible results.
Answer:
Yes! With superior separation power and precision, LECO’s GC×GC-TOFMS system can uncover hidden details and confidently identify components, even in the most intricate mixtures:
- Increases detectability
- Removes analytes from matrix interference
- Separates co-elluting peaks
- Creates cleaner peaks, which match closer with libraries
- Creates structured chromatograms thus further improving identification confidence
Answer:
The cryogenic Quad Jet modulator consistently delivers reproducible quantitative results not only within the lab but also between labs worldwide. This is achieved because:
- There are two cold jets. So, eluent from the primary column does not flow into the secondary column by mistake
- The distance between cold zones is identical in every system worldwide, unlike other systems that require manual adjustment and intervention
- The modulation is completely computer controlled. This along with the 2 separate cold zones, allows for variable modulation periods in the same analysis, vastly improving separation across the chromatogram
- In the same way the primary column is temperature controlled in the primary oven, the secondary column is also independently controlled, allowing for total control of the chromatogram along the entire column setup
These four features not only improve separation and control, they are also unique to the LECO QuadJet.
Answer:
By combining comprehensive two-dimensional gas chromatography (GC×GC) with high-speed, high-sensitivity time-of-flight mass spectrometry (TOFMS), LECO's GC×GC-TOFMS can separate and identify the complex mixtures of flavours and fragrances in food samples with detail and precision.
Answer:
Yes! LECO’s GC×GC-TOFMS is an excellent tool for non-intentionally added substances (NIAS) analysis in food safety. It allows for the comprehensive analysis of complex food samples, ensuring the detection and identification of potential contaminants and unwanted substances. For example, LECO’s MOSH/MOAH solution is widely recognised as the most comprehensive and rigorous analyser for mineral oil contamination in food stuffs.
Answer:
LECO’s GC×GC technology utilizes two stages of separation, significantly increasing resolution and analysis power compared to traditional gas chromatography. This allows for the detailed separation and identification of complex mixtures with unparalleled precision.
Answer:
LECO’s TOFMS technology offers excellent sensitivity, speed, and resolution in mass spectrometry. By fragmenting and ionizing analyte molecules and separating the fragments based on their mass-to-charge ratio, LECO's TOFMS enables highly accurate identification and detection of compounds in samples. The system not only records to a computer at high speed, it detects at a rate of 32,000 Hz thus producing a very high level of accuracy.
Answer:
GC×GC-TOFMS enables the analysis of dietary supplements for the presence of non-compliant ingredients, such as animal-derived gelatine, ensuring that the products meet the strict requirements of Halal certification.
Answer:
GC×GC-TOFMS is a valuable tool for monitoring air and soil quality near Islamic sacred sites, identifying pollutants that may pose a risk to their preservation and guiding conservation efforts. As an example, Imperial College London have utilised a LECO Pegasus BT 4D to identify microplastics in the air of London. You can read about it here.
Answer:
LECO’s GC×GC-TOFMS system utilizes Time-of-Flight Mass Spectrometry (TOFMS), which provides high-speed detection of ionized compounds based on their mass-to-charge ratio.
Answer:
LECO provides software for data analysis, enabling compound identification, quantification, and other types of analysis based on the mass spectra obtained from the TOFMS.
Answer:
LECO’s StayClean ion source, a standard feature in every Pegasus BT GC-TOFMS and GC×GC-TOFMS system, flushes neutrals and contaminants continuously. This virtually eliminates the need for routine maintenance, allowing you to spend less time on upkeep and more time on your research.
Answer:
Sample handling is crucial in GC-MS analysis. LECO employs advanced sample handling robots called Autosamplers that can handle samples in three dimensions of space. These robots ensure precise and consistent sample preparation, ranging from simple liquid injections to complex processes like chemical reactions, extractions, and accurate dilutions.
Answer:
The first GC-MS was a GC-TOFMS developed in the 1950s. However, the technique was too powerful for data recording at the time. In the mid-1990s the first GC-TOFMS capable of recording the data for processing was developed by LECO. This breakthrough in fast GC-TOFMS technology allowed researchers and analysts to utilize the capabilities of GC-TOFMS for their analytical needs.
Answer:
By combining two-dimensional separation, robust ionization, and high-speed TOFMS detection, and patented deconvolution algorithms LECO's GC×GC-TOFMS system offers a powerful solution for analysing complex mixtures with enhanced resolution, sensitivity, and separation power.
Answer:
By analysing the chemical composition of materials used in ancient Islamic artifacts, GC×GC-TOFMS assists in determining their authenticity, providing valuable insights into historical and cultural heritage. The chemical composition of such artifacts are extremely complex so utilising multidimensional chromatography techniques with high speed TOFMS, a chemical profile can be created. Furthermore, LECO’s post processing software packages, ChromaTOF Tile and ChromaTOF Sync can identify differences between samples to compare artifacts and identify biomarkers.
Let LECO help you
find the right instruments for your needs.
Se desideri saperne di più sui nostri prodotti e le nostre soluzioni per l’analisi degli alimenti, prenota un biglietto gratuito per la nostra fiera virtuale o pianifica una demo online per fare un’analisi più approfondita dei nostri strumenti.
Explore the Fascinating World of Separation Science
The very first GC-MS was a GC-TOFMS which was built in 1947. The information it provided was much too large to record, and it was not until the mid-1990s when LECO introduced the first fast GC-TOFMS, that GC-TOFMS became a useable tool for researchers and analysts. Followed a few years later by LECO’s introduction of the first GC×GC-TOFMS.
Today, LECO’s Separation Science products are recognised across the globe as leading advanced technology innovations in TOFMS Mass Spectrometry and Comprehensive two-dimensional Chromatography.
PEGASUS® BT GC-TOFMS
GC Time-Of-Flight Mass Spectrometer
Today‘s laboratories are being asked for more everyday – more samples run, more data acquired, more chemical information processed, and more results achieved – all in less time, for less money. ...
The Pegasus BT allows you to achieve all you need from a single sample run, while powerful and user-friendly ChromaTOF® software processes your data and removes the guesswork involved with analyte identification, quantitation, and reporting. The Pegasus BT gives users more uptime, better data, and an increase in overall productivity and efficiency.
Uno spettrometro di massa a tempo di volo (TOFMS) è l'ideale per scoprire nuovi composti nel campione, quantificare i composti target in campioni complessi e aumentare la produttività con la cromatografia rapida.
► Download the free whitepaper and brochure
PEGASUS® BT 4D GC×GC-TOFMS
GC×GC Time-Of-Flight Mass Spectrometer
The Pegasus BT 4D offers enhanced sensitivity by coupling our benchtop Pegasus BT with a high-performance GC×GC modulation system. This combination gives the Pegasus BT 4D the ability to interrogate challenging samples ...
... where the best sensitivity is needed. Le funzionalità software e hardware uniche e potenti semplificano la quantificazione, permettono inoltre che GCxGC sia incredibilmente facile da utilizzare e da comprendere. Our thermal modulation system, the QuadJet™, is recognised as the gold standard in GC×GC modulation, providing the highest sensitivity available on the market - ideal for analysing the most complex samples.
One of the main advantages of LECO’s GC×GC-TOFMS is its ability to provide vastly improved peak capacity and resolution than traditional GC-MS systems. It also offers comprehensive information about the sample by separating compounds based on two different properties (volatility and polarity). Combining GC×GC with TOFMS is an ultimate solution for the analysis of complex samples.
► Download the free brochure
PEGASUS® GC-HRT+
High Resolution Time-Of-Flight Mass Spectrometer
Now with even more sensitivity than ever before, the Pegasus GC-HRT+ is the perfect tool for meeting the challenges of today’s highly complex analytical demands. ...
This high-resolution mass spectrometer features industry leading mass accuracy, full mass range acquisition with exceptional speed, full mass range acquisition with exceptional speed, isotopic abundance and mass resolution, all available in a single injection.
Folded Flight Path® (FFP®) technology and a novel data acquisition system enables simultaneous resolutions of over 50,000 FWHM, mass accuracies less than 1 ppm, and acquisition rates up to 200 spectra/second, without the need to adjust tuning or parameters. Thus, facilitating rich analyte finding and high-confidence analyte identification.
► Download the free brochure
PEGASUS® GC-HRT+ 4D
HR GC×GC Time-Of-Flight Mass Spectrometer
The Pegasus GC-HRT+ 4D combines the highest performance GC×GC and TOFMS tools on the market with High Resolution Deconvolution® (HRD®). Ideal for the most complex samples, ...
... users are able to find more analytes than ever before and confidently identify unknown components.
The Pegasus GC-HRT+ 4D takes advantage of four dimensions of separation and resolution:
- 1st dimension chromatographic resolution
- 2nd dimension chromatographic resolution
- High mass resolution and exceptional mass accuracy
- High Resolution Deconvolution (HRD) from the leaders in deconvolution
ChromaTOF brand software, designed specifically for HRT+ instrumentation and GC×GC support, adds advanced qualitative and quantitative capabilities to an all-in-one user-friendly data system.
► Download the free brochure
Examples of LECO Separation Science Applications
Petrolio
Comprehensive Two-Dimensional Gas Chromatography (GC×GC) has proven to be an extremely valuable analytical technique for the petroleum industry due to its ability to substantially increase the chromatographic peak capacity beyond that of traditional single-dimension gas chromatography. Pairing GC×GC with Time-of Flight Mass Spectrometry (TOFMS) provides unsurpassed characterization capabilities due to the separation power of GC×GC and the ability of TOFMS to provide rich data.
Food Testing
The characterization and safety testing of food and food constitutions can be extremely challenging depending on the complexity and the matrix. The LECO GC×GC TOFMS technology provides a highly powerful separation and remarkable identification allowing for improved workflows. More insights thanks to the advanced technology in combination with LECO’s ChromaTOF® brand software deconvolution algorithm and advanced data analysis tool will improve your Food Quality & Safety Testing and Food R&D. Here we demonstrate the aroma analsyis of two types of coffee and coffee packaging and filter leachates.
Perfume and Cosmetics
LECO‘s GC×GC-TOFMS is a valuable asset in the production of cosmetics and perfumes that align with Islamic principles. It can be used to identify the ingredients and detect any prohibited substances such as alcohol or non-halal animal-derived ingredients.
Analisi ambientale
Microplastics are an emerging pollutant which are widely distributed in the environment. Understanding the impact of their growing prevalence on the environment and human health is an important field of research. LECO‘s GC×GC-TOFMS can be used to monitor environmental pollution and air and water quality thus aiding to enforce regulations and ensure the preservation of our environment.
Metabolomica
LECO’s key advantage is the ability to identify and discover more metabolites than other similar technologies. La nostra velocità di acquisizione della scansione completa non ha rivali e, se combinata con la potenza dell'algoritmo di deconvoluzione del marchio software ChromaTOF®, consente una caratterizzazione dei sistemi biologici allo studio. La nostra strumentazione è stata validata dai ricercatori più esigenti del settore.
Extractables and Leachables
The characterization of extractable and leachable components from a wide range of materials is an important area of research. Information about extractable and leachable components from packaging and delivery devices for pharmaceutical products is a particular area of growing interest. Analytical testing results on this topic are part of many regulatory submission requirements to the FDA. ...
USP 1663 provides guidance on extractables testing and a variety of analytical approaches can meet compliance. High resolution MS is often considered necessary for identification of unknowns, and sample complexity and low-level detection continue to challenge these analyses. Here, we demonstrate a workflow that uses comprehensive two-dimensional gas chromatography (GC×GC) with HR-TOFMS to help address these challenges.
► App Note | Characterizing Extractables by GC×GC & HR-TOFMS
FAQ – Separation Science
Answer:
Gas chromatography separates components in a mixture by utilizing a thin silica tube coated with a stationary phase. The components, carried by a gas (the mobile phase), move at different speeds based on their affinities for the stationary phase. This differential migration leads to the separation of the components, allowing for their individual analysis and identification.
Alternative response:
- Gas chromatography is a technique for separating a mixture of volatile analytes
- The analytes are transported by a mobile phase (the carrier gas)
- Become distributed between the mobile phase and a stationary phase
- The Stationary Phase is attached to the inside of a very fine column
- Phases are typically characterised by their polarity
- A polar analyte will be retained by polar column for longer than a non-polar analyte
- and vica versa
Answer:
LECO uses Agilent 8890 chromatography. The gas chromatograph includes the following features:
- Compatibility and perfect integration with the mass spectrometer
- Automatic regulation of gas flows
- Agilent supported inlets: Split/Splitless (SSL), Multimode (MMI), Programmable temperature Vaporizer (PTV) etc.
- Programmable oven, up to 450 °C
- Chromatograph compatible with Fast-GC
- The GC is completely controlled by and integrated into LECO’s ChromaTOF software
Answer:
The LECO mass spectrometer is connected to the GC via a heated transfer line. The LECO GC-TOF allows you to have a 'full range' acquisition, without compromise, then a targeted and/or non-targeted data exploitation depending on what you want to do.
It consists of an EI (Electronic Impact) source, a 70 cm flight tube, a reflectron and a detector. Vacuum is provided by an internal turbomolecular pump connected to an external secondary pump.
Answer:
The mass range of the Pegasus BT is from 10 to 1500 m/z. All masses are collected all the time, unlike quadrupole instruments that collect a single mass at a time (quadrupole scanning mode is single ion monitoring, SIM, quickly scanning across the mass range).
Answer:
GC×GC-TOFMS can detect discrepancies in the composition of food products, helping to expose fraudulent claims of Halal certification and ensure consumer confidence in authentic Halal products.
Answer:
By examining the chemical composition of inks and pigments, GC×GC-TOFMS provides insights into the materials used in Islamic calligraphy and manuscripts, aiding in their preservation and authentication. An example of similar work can be read in this publication on analysing the paints used by Leonardo Da Vinci.
Answer:
LECO’s GC×GC-TOFMS system utilizes two columns with different separation mechanisms, providing enhanced chromatographic resolution for the analysis of complex mixtures. In one dimension the analytes are separated by polarity, or according to boiling point. An additional dimension separates according to an alternative property, of which there are many. This results in a 3D image – the two dimensions of separation and the abundance of the analytes in the third dimension.
Answer:
LECO's StayClean® ion source originates in the requirement for a fast source to match the speed of the TOFMS. Accomplished by reducing ion to ion interactions, such as with the walls of the source. The source was thus designed without walls – so there is nothing to clean. Massively reduced downtimes, especially for complex matrices and more reproducible results.
Answer:
Yes! With superior separation power and precision, LECO’s GC×GC-TOFMS system can uncover hidden details and confidently identify components, even in the most intricate mixtures:
- Increases detectability
- Removes analytes from matrix interference
- Separates co-elluting peaks
- Creates cleaner peaks, which match closer with libraries
- Creates structured chromatograms thus further improving identification confidence
Answer:
The cryogenic Quad Jet modulator consistently delivers reproducible quantitative results not only within the lab but also between labs worldwide. This is achieved because:
- There are two cold jets. So, eluent from the primary column does not flow into the secondary column by mistake
- The distance between cold zones is identical in every system worldwide, unlike other systems that require manual adjustment and intervention
- The modulation is completely computer controlled. This along with the 2 separate cold zones, allows for variable modulation periods in the same analysis, vastly improving separation across the chromatogram
- In the same way the primary column is temperature controlled in the primary oven, the secondary column is also independently controlled, allowing for total control of the chromatogram along the entire column setup
These four features not only improve separation and control, they are also unique to the LECO QuadJet.
Answer:
By combining comprehensive two-dimensional gas chromatography (GC×GC) with high-speed, high-sensitivity time-of-flight mass spectrometry (TOFMS), LECO's GC×GC-TOFMS can separate and identify the complex mixtures of flavours and fragrances in food samples with detail and precision.
Answer:
Yes! LECO’s GC×GC-TOFMS is an excellent tool for non-intentionally added substances (NIAS) analysis in food safety. It allows for the comprehensive analysis of complex food samples, ensuring the detection and identification of potential contaminants and unwanted substances. For example, LECO’s MOSH/MOAH solution is widely recognised as the most comprehensive and rigorous analyser for mineral oil contamination in food stuffs.
Answer:
LECO’s GC×GC technology utilizes two stages of separation, significantly increasing resolution and analysis power compared to traditional gas chromatography. This allows for the detailed separation and identification of complex mixtures with unparalleled precision.
Answer:
LECO’s TOFMS technology offers excellent sensitivity, speed, and resolution in mass spectrometry. By fragmenting and ionizing analyte molecules and separating the fragments based on their mass-to-charge ratio, LECO's TOFMS enables highly accurate identification and detection of compounds in samples. The system not only records to a computer at high speed, it detects at a rate of 32,000 Hz thus producing a very high level of accuracy.
Answer:
GC×GC-TOFMS enables the analysis of dietary supplements for the presence of non-compliant ingredients, such as animal-derived gelatine, ensuring that the products meet the strict requirements of Halal certification.
Answer:
GC×GC-TOFMS is a valuable tool for monitoring air and soil quality near Islamic sacred sites, identifying pollutants that may pose a risk to their preservation and guiding conservation efforts. As an example, Imperial College London have utilised a LECO Pegasus BT 4D to identify microplastics in the air of London. You can read about it here.
Answer:
LECO’s GC×GC-TOFMS system utilizes Time-of-Flight Mass Spectrometry (TOFMS), which provides high-speed detection of ionized compounds based on their mass-to-charge ratio.
Answer:
LECO provides software for data analysis, enabling compound identification, quantification, and other types of analysis based on the mass spectra obtained from the TOFMS.
Answer:
LECO’s StayClean ion source, a standard feature in every Pegasus BT GC-TOFMS and GC×GC-TOFMS system, flushes neutrals and contaminants continuously. This virtually eliminates the need for routine maintenance, allowing you to spend less time on upkeep and more time on your research.
Answer:
Sample handling is crucial in GC-MS analysis. LECO employs advanced sample handling robots called Autosamplers that can handle samples in three dimensions of space. These robots ensure precise and consistent sample preparation, ranging from simple liquid injections to complex processes like chemical reactions, extractions, and accurate dilutions.
Answer:
The first GC-MS was a GC-TOFMS developed in the 1950s. However, the technique was too powerful for data recording at the time. In the mid-1990s the first GC-TOFMS capable of recording the data for processing was developed by LECO. This breakthrough in fast GC-TOFMS technology allowed researchers and analysts to utilize the capabilities of GC-TOFMS for their analytical needs.
Answer:
By combining two-dimensional separation, robust ionization, and high-speed TOFMS detection, and patented deconvolution algorithms LECO's GC×GC-TOFMS system offers a powerful solution for analysing complex mixtures with enhanced resolution, sensitivity, and separation power.
Answer:
By analysing the chemical composition of materials used in ancient Islamic artifacts, GC×GC-TOFMS assists in determining their authenticity, providing valuable insights into historical and cultural heritage. The chemical composition of such artifacts are extremely complex so utilising multidimensional chromatography techniques with high speed TOFMS, a chemical profile can be created. Furthermore, LECO’s post processing software packages, ChromaTOF Tile and ChromaTOF Sync can identify differences between samples to compare artifacts and identify biomarkers.
Let LECO help you
find the right instruments for your needs.
Se desideri saperne di più sui nostri prodotti e le nostre soluzioni per l’analisi degli alimenti, prenota un biglietto gratuito per la nostra fiera virtuale o pianifica una demo online per fare un’analisi più approfondita dei nostri strumenti.
Expedite Gas Chromatography Analysis with Hydrogen
For years, helium has been the go-to choice as a carrier gas for mass spectrometers due to its well-known benefits. However, its limited supply and varying costs have posed significant challenges for labs worldwide.
LECO has conducted extensive research on the use of hydrogen as a carrier gas for GC-TOFMS analysis. We have developed innovative method transfer approaches to ensure a smooth and efficient transition to hydrogen. With our proven expertise in the hydrogen conversion process, we can help labs of all sizes achieve increased chromatographic throughput without sacrificing the sensitivity and accuracy they demand.
As the supply of helium continues to dwindle, the use of hydrogen as a carrier gas for GC applications has become an increasingly attractive option. With both benefits and drawbacks to consider, it requires the expertise of a dedicated team to determine the optimal approach.
In the following sections, we will share the details of our approach, including the method transfer approaches used, the technological benefits, and application examples. At LECO, we understand the importance of providing comprehensive information and support. That's why we have put together a range of resources specifically on hydrogen conversion, to help you make an informed decision.
Don‘t miss out on this unique opportunity!
We know how valuable your time is, so we‘re bringing the experts and resources closer to you to show you how LECO instrumentation and hydrogen carrier gas can revolutionize your analysis, with live demos of our instruments and software.
Instrument Portfolio for Hydrogen carrier gas
We understand that the conversion from helium to hydrogen carrier gas can be a crucial step in mass spectrometry, where speed and sensitivity are of utmost importance. At LECO, we take pride in designing our PEGASUS® mass spectrometers to deliver exceptional performance in Fast GC applications with both helium and hydrogen carrier gas. Our instruments are built to provide high-speed analysis without compromising sensitivity, making them the ideal choice for labs looking to switch to hydrogen. In addition, with our innovative StayClean® Ion Source technology, you can be confident that your instrument will operate at peak efficiency, free from the need for frequent cleaning and maintenance.
On-demand Videos & Presentations
Helium is becoming an increasingly limited natural resource; using Hydrogen to achieve increased chromatographic throughput in GC applications is attractive. Both have advantages and disadvantages. LECO has for years investigated the use of Hydrogen as a carrier gas for GC-TOFMS analysis. In the following we are going to present you the method transfer approaches used, the technological benefits, and application examples.
► „Fast GC / Hydrogen Method Transfer Overview & Application Examples“
by Nick Jones, Sebastiano Panto, Lena Dubois, Joe Binkley (LECO Corporation, St. Joseph, MI USA)
Please click here for watching the video ...
► „GC×GC Analysis with Chroma TOF Tile“
by Lena Dubois (LECO ETAC, Berlin, GER)
Please click here for watching the video ...
► „GC-MS Analysis Workflow utilizing ChromaTOF Sync“
by Liz Humstom-Fulmer (LECO Corporation, St. Joseph, MI USA)
Please click here for watching the video ...
► „Discovery Workflow Best Practices for Environmental Contaminants“
by Albert T. Lebedev (Lomonosov Moscow State University), David E. Alonso (LECO Corporation, St. Joseph, MI USA)
Please click here for watching the video ...
Webinar: Enhance Your GC-MS Workflow
With ever-increasing demands on your time, labor, and resources, optimizing your workflow is essential. Learn best approaches from GC-TOFMS experts to enhance your one- and two-dimensional gas chromatography applications (GC-MS and GC×GC-MS) in this webinar.
Webinar: Designed for Speed – A Fast GC Forum
Could your lab use to speed up your GC analysis? In the „Designed for Speed“ forum, a panel of experts explore advancements in gas chromatography and mass spectrometry technology and how laboratories can speed up their analysis.
Library – Hydrogen Carrier Gas Publications
Read our following publications and discover more about GC-TOFMS analyses with hydrogen as a carrier gas.
Thank you for submitting the form. You now have access to all files.
App Notes:
Hydrogen-based GC-TOFMS Analysis
The shortage of helium and its increased costs are encouraging laboratories to find suitable alternatives. Learn how LECO achieves quality results utilizing Hydrogen as a carrier gas.
Poster:
„Utilizing unique TOF-MS technology and hydrogen carrier gas for fast GC-MS“
How many sample runs can you fit into your day? With a few simple changes, LECO‘s Pegasus BT can drastically speed up gas chromatography throughput. A faster time-of-flight analysis doesn‘t need to mean lower quality results.
Article:
„A green and sustainable method for Capsicum [...] using H2 Carrier Gas“
Learn how scientists from the University of Messina (Italy) increased their sustainability and „greenified“ their pepper analyses utilizing LECO separation science instruments.
Sei interessato?
We welcome the opportunity to discuss how hydrogen conversion can benefit your lab.
Get in touch with us today to learn more.
If you want to learn more about our products and solutions for Fast GC analysis, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
Expedite Gas Chromatography Analysis with Hydrogen
For years, helium has been the go-to choice as a carrier gas for mass spectrometers due to its well-known benefits. However, its limited supply and varying costs have posed significant challenges for labs worldwide.
LECO has conducted extensive research on the use of hydrogen as a carrier gas for GC-TOFMS analysis. We have developed innovative method transfer approaches to ensure a smooth and efficient transition to hydrogen. With our proven expertise in the hydrogen conversion process, we can help labs of all sizes achieve increased chromatographic throughput without sacrificing the sensitivity and accuracy they demand.
As the supply of helium continues to dwindle, the use of hydrogen as a carrier gas for GC applications has become an increasingly attractive option. With both benefits and drawbacks to consider, it requires the expertise of a dedicated team to determine the optimal approach.
In the following sections, we will share the details of our approach, including the method transfer approaches used, the technological benefits, and application examples. At LECO, we understand the importance of providing comprehensive information and support. That's why we have put together a range of resources specifically on hydrogen conversion, to help you make an informed decision.
Don‘t miss out on this unique opportunity!
We know how valuable your time is, so we‘re bringing the experts and resources closer to you to show you how LECO instrumentation and hydrogen carrier gas can revolutionize your analysis, with live demos of our instruments and software.
Instrument Portfolio for Hydrogen carrier gas
We understand that the conversion from helium to hydrogen carrier gas can be a crucial step in mass spectrometry, where speed and sensitivity are of utmost importance. At LECO, we take pride in designing our PEGASUS® mass spectrometers to deliver exceptional performance in Fast GC applications with both helium and hydrogen carrier gas. Our instruments are built to provide high-speed analysis without compromising sensitivity, making them the ideal choice for labs looking to switch to hydrogen. In addition, with our innovative StayClean® Ion Source technology, you can be confident that your instrument will operate at peak efficiency, free from the need for frequent cleaning and maintenance.
On-demand Videos & Presentations
Helium is becoming an increasingly limited natural resource; using Hydrogen to achieve increased chromatographic throughput in GC applications is attractive. Both have advantages and disadvantages. LECO has for years investigated the use of Hydrogen as a carrier gas for GC-TOFMS analysis. In the following we are going to present you the method transfer approaches used, the technological benefits, and application examples.
► „Fast GC / Hydrogen Method Transfer Overview & Application Examples“
by Nick Jones, Sebastiano Panto, Lena Dubois, Joe Binkley (LECO Corporation, St. Joseph, MI USA)
Please complete our form to watch the videos on-demand.
► „GC×GC Analysis with Chroma TOF Tile“
by Lena Dubois (LECO ETAC, Berlin, GER)
Please complete our form to watch the videos on-demand.
► „GC-MS Analysis Workflow utilizing ChromaTOF Sync“
by Liz Humstom-Fulmer (LECO Corporation, St. Joseph, MI USA)
Please complete our form to watch the videos on-demand.
► „Discovery Workflow Best Practices for Environmental Contaminants“
by Albert T. Lebedev (Lomonosov Moscow State University), David E. Alonso (LECO Corporation, St. Joseph, MI USA)
Please complete our form to watch the videos on-demand.
Webinar: Enhance Your GC-MS Workflow
With ever-increasing demands on your time, labor, and resources, optimizing your workflow is essential. Learn best approaches from GC-TOFMS experts to enhance your one- and two-dimensional gas chromatography applications (GC-MS and GC×GC-MS) in this webinar.
Webinar: Designed for Speed – A Fast GC Forum
Could your lab use to speed up your GC analysis? In the „Designed for Speed“ forum, a panel of experts explore advancements in gas chromatography and mass spectrometry technology and how laboratories can speed up their analysis.
Library – Hydrogen Carrier Gas Publications
Read our following publications and discover more about GC-TOFMS analyses with hydrogen as a carrier gas. We kindly ask you to submit our form. Afterwards you‘ll get access to all files.
App Notes:
Hydrogen-based GC-TOFMS Analysis
The shortage of helium and its increased costs are encouraging laboratories to find suitable alternatives. Learn how LECO achieves quality results utilizing Hydrogen as a carrier gas.
„Analsysis of Teatree Oil“
„Citrus Essential Oils“
Poster:
„Utilizing unique TOF-MS technology and hydrogen carrier gas for fast GC-MS“
How many sample runs can you fit into your day? With a few simple changes, LECO‘s Pegasus BT can drastically speed up gas chromatography throughput. A faster time-of-flight analysis doesn‘t need to mean lower quality results.
Article:
„A green and sustainable method for Capsicum [...] using H2 Carrier Gas“
Learn how scientists from the University of Messina (Italy) increased their sustainability and „greenified“ their pepper analyses utilizing LECO separation science instruments.
Sei interessato?
We welcome the opportunity to discuss how hydrogen conversion can benefit your lab.
Get in touch with us today to learn more.
If you want to learn more about our products and solutions for Fast GC analysis, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
Attention All Aroma Enthusiasts!
The LECO Aroma Roadshow 2023 has concluded, and it was a remarkable journey that brought the world of aroma analysis closer to professionals across Europe. At LECO, we understand the value of your time, and our goal was to make expertise more accessible. We're thrilled to have had the opportunity to meet with you in person and demonstrate how LECO instrumentation and the use of hydrogen carrier gas can elevate your analytical capabilities.
Our team of friendly and knowledgeable application specialists provided live demonstrations of our cutting-edge instruments and software, enriching your understanding of aroma analysis. We are grateful for your active participation and insightful questions, which made this event a success.
While the LECO Aroma Roadshow 2023 has concluded, our commitment to advancing your knowledge and expertise continues. Stay tuned for more updates, resources, and future events from LECO
For any questions or further information, please contact: Questo indirizzo e-mail è protetto dagli spambot. Abilitare Javascript per visualizzarlo.
More about aroma analysis
If you missed our roadshow and want to delve deeper into the world of aroma analysis, please visit our aroma resources page. There, you'll find valuable insights and information to enhance your understanding of this fascinating field.
Program
At the LECO Aroma Roadshow, each event stop was thoughtfully designed to maximize the experience and deliver valuable insights for all attendees. The goal was to make the most of everyone's precious time.
During the dedicated time slots, our experts provided one-on-one assistance, addressing specific needs and answering questions that arose. Attendees had the chance to witness our instruments in action, all without disrupting their busy schedules.
The event was a collaborative exploration of data, where participants saved time and gained valuable insights. It was a unique opportunity for personalized guidance from experts tailored to sample data.
Please click on the image to enlarge.
Come possiamo farlo?
LECO instrumentation is robust and reliable, allowing us to set up methods in advance that will run in any environment.
Using hydrogen carrier gas vastly speeds up the acquisition process reducing run times by up to 75%.
The instrument will be set up to run your sample allowing our conversation to revolve around your data.
Sample
Our Sales Engineer will be in contact with you and will provide instructions on how to prepare your samples for live measurements. They will provide all the necessary information and collaborate with our team of application specialists to help you achieve exceptional results. With the goal of empowering your results, we're committed to ensuring your measurements are accurate and reliable. Should you not have specific requests, our team will also prepare test samples for measurement.
Roadshow Venues
Completed
18th or 19th April
Stockport, UK
LECO Instruments Ltd.
Unit 7, Rhino Court, Station View
Bramhall Moor Lane, Hazel Grove
Stockport SK7 5ER
Completed
26th or 27th April
Cambridge, UK
Element Cambridge
(formerly Anatune)
Unit 4, Wellbrook Court
Girton Rd, Girton
Cambridge CB3 0NA
Completed
2th or 3th May
Oberhausen, GER
SIM Scientific Instruments
Manufacturer GmbH
Im Erlengrund 21-23
46149 Oberhausen
Completed
25th or 26th May
Ferrara, IT
University of Ferrara
Via Luigi Borsari, 46
44121 Ferrara FE
Completed
25th or 26th May
Berlin, GER
LECO EATC
Max-Dohrn Strasse 8-10
Biotechpark, Building B 5.2
10589 Berlin
Completed
7th or 8th June
Liège, BEL
University of Liège
Place du 20 Août 7
4000 Liège
Completed
29th or 30th June
Lione, FR
Université de Lyon
92 Rue Pasteur
69007 Lyon
Completed
12th September
Messina, IT
Università degli Studi di Messina
Via G. Palatucci SNC
98168 Messina
Completed
14th or 15th November
Berlin, GER
LECO EATC
Max-Dohrn Strasse 8-10
Biotechpark, Building B 5.2
10589 Berlin
Let LECO help you find the right instruments for your need.
Se desideri saperne di più sui nostri prodotti e le nostre soluzioni per l’analisi degli aromi, prenota un biglietto gratuito per la nostra fiera virtuale o pianifica una demo online per fare un’analisi più approfondita dei nostri strumenti.
Enhance your Food Analysis
Gli strumenti LECO analizzano la qualità, la sicurezza e il valore nutritivo di molti alimenti e mangimi, dagli alimenti crudi ai prodotti pronti per il consumatore finale. Benefit fom the advantages of our state-of-the-art solutions for your individual food analysis. Elevate your results and save your time.
Specific Advantages Including
- Moisture Determination – Loss on drying automated up to 16 samples simultaneously
- MOSH/MOAH Determination – Identify and quantify the source of contamination
- Detection of Pesticides – Even in the most difficult matrices
- Protein Determination after Dumas – Replacement of Kjeldahl; Results in ≈ 3 minutes fully matrix independent
- Aroma Profiling – Identify what you smell, but never see
Unlock the 2023 special issue of FoodLab Magazine now – Exclusively Available Here!
Explore our exclusive collection of expert articles on aroma, moisture & ash, MOSH/MOAH, and protein, developed in collaboration with FoodLab Magazine. Download now for the latest insights in the food industry.
Instrument Portfolio for Food Analysis
Your Solution For Cost Effective Food Analysis
Check out our broad product portfolio for food safety, nutrition, and moisture analysis. Benefit from the advantages of our state-of-the-art solutions for your individual food analysis.
MOSH MOAH Determination
Qualunque siano i requisiti per la preparazione del campione, sfrutta la potenza della tecnologia LECO GCxGC & TOF per risolvere le complesse sfide dell'analisi MOSH/MOAH.
Determinazione delle proteine
Protein determination with LECO after the principle of Dumas can be very easy and convenient. LECO has the perfect solution with the 828 and the 928 productline.
Determination of Moisture/Ash/Loss on Drying
An accurate determination of moisture content in food or agricultural products provides important information related to the food quality and safety.
Aroma Analysis
Quantificare e schermare i campioni con una singola iniezione utilizzando la spettrometria di massa a tempo di volo di cromatografia gassosa bidimensionale LECO (GCxGC TOFMS).
White Paper | Protein Analysis - Dumas Vs. Kjeldahl
Have you ever wondered about this old discussion about „Dumas and Kjedahl“ and which one fits better to your needs in the field of protein analysis?
Read our lates white paper related to protein analysis by comparing the methods "Dumas vs. Kjeldahl". Get a concise overview about the theories of operation, and learn how the benefits of a LECO Dumas determinator can impact your workflow.
Let LECO help you find the right instruments for your needs.
Se desideri saperne di più sui nostri prodotti e le nostre soluzioni per l’analisi degli alimenti, prenota un biglietto gratuito per la nostra fiera virtuale o pianifica una demo online per fare un’analisi più approfondita dei nostri strumenti.
LA2PC | LECO Analytical Applications Poster Competition
With the aim of improving our understanding and knowledge of LECO users’ work and research, LECO Europe hosted the LECO Analytical Poster Competition 2020. It was very successful, as we received a variety of interesting posters from our LECO users and customers featuring various applications and fields of interest. Please see below all entries in the different fields. For a higher resolution please complete our login-form. To download the complete poster booklet with all submissions, please click on the button below.
Elemental Analysis Entries
"Macro, micro? Comparison of DUMAS analysers in real conditions"
Jean-Michel Romnee | CRAW, Walloon Agricultural Research Centre
Charles Ojeimi | ELEMENTAR France
Alexis Sorokovsky | LECO France
Please click here to view high-resolution.
"Trumac CN, a tool to evaluate the quality of fertilizers humic coating"
Jean-Michel Romnee | CRAW, Walloon Agricultural Research Centre
Please click here to view high-resolution.
"IGA Fractional O/N/H Analyses of Powder Feedstocks for Additive Manufacturing"
Boris Albouy, Jérémy Berot-Lartigue, Nicole Cuq, Xinwei Wang | Eurofins EAG Laboratories
Please click here to view high-resolution.
"Analysis of Tic-based Alloys Prepared by Mechanical Alloying and Spark Plasma Sintering"
Mohsen Mhadhbi | National Institute of Research and Physical-Chemical Analysis
Frédéric Schoenstein, Noureddine Jouini | Paris 13 University
Please click here to view high-resolution.
"Development of a method to analyze Aluminum alloys powders using the gas analyzer LECO ONH836"
Jimmy Dardinier, Thibaut Turlan, Agathe Deborde | MetaFensch, IRT-M2P
Please click here to view high-resolution.
"LECO Boat Crucible as an Aid to Analysis of Total Organic Carbon (TOC) Content in Rock Samples"
Doaa A. Mousa, Shereen A. Naseef, Amr M. Shehata | Egyptian Petroleum Research Institute (EPRI)
Please click here to view high-resolution.
"LECO Spectrum System 2000"
Walid A. Makled | Egyptian Petroleum Research Institute (EPRI)
Please click here to view high-resolution.
“Pretrattamento dei rifiuti di biomassa lignocellulosica per la nuova generazione di combustibili solidi”
Karl Hornsby, Martin J. Taylor, Vasiliki Skoulou | University of Hull
Peter Hurst | Biorenewables Development Centre (BDC)
Simon Walker | Jesmond Engineering Ltd, Brough Business Centre
Please click here to view high-resolution.
"Moisture, Volatiles and Ash in Biofuels with the TGA801"
[No Competitor] Michael Jakob | LECO EUROPE
Please click here to view high-resolution.
Documenti della scienza della separazione
"VOCs from Wood Fibers Insulation Materials"
Dorota Fuczek, Jaroslaw Szuta, Krystian Szutkowski | STEICO Sp. z o.o.
Please click here to view high-resolution.
"Analytical Pyrolysis Coupled with Chemometric Methods"
Marcin Sajdak, Roksana Muzyka, Maciej Chrubasik | Institute for Chemical Processing of Coal
Please click here to view high-resolution.
"Investigation of Baijiu Aroma Types and Regional Origin"
Xi He, Henryk. H. Jelen | Poznan University of Life Sciences
Please click here to view high-resolution.
"Pyro-GC×GC-TOFMS/FID for the study of organic matter in unconventional hydrocarbon reservoirs"
E. Leushina, E. Kozlova, T. Bulatov, M. Spasennykh | Skoltech
Please click here to view high-resolution.
"Detection of Honey Bee Disease Through Monitoring Shifts in Volatile Profiles"
Margaret Gill, Falko Drijfhout | Keele University
Please click here to view high-resolution.
"Green and Sustainable Catalysis Using a Pd Doped Biochar under Mild Conditions"
Jamie P. Southouse, Karl Hornsby, Kin Wai Cheah, M. Grazia Francesconi, Vasiliki Skoulou, Martin J. Taylor | University of Hull
Please click here to view high-resolution.
Se desideri conoscere di più dei nostri prodotti e delle nostre soluzioni per il tuo laboratorio prenota un biglietto gratuito per la Fiera Virtuale LECO, che offre una visione approfondita dei nostri strumenti.
La metabolomica rappresenta una sfida sia per i metodi analitici utilizzati, che per la riduzione dei dati necessaria all'interpretaizone dei risultati. Nessuna tecnica analitica singola può essere utilizzata per la caratterizzazione completa del metaboloma, e nessun metaboloma è stato completamente caratterizzato. Tuttavia la GC-MS fornisce un metodo consolidato per analizzare il metaboloma primario, mentre la LC indaga sui metaboliti secondari e terziari.
Soluzioni LECO per l'analisi degli aromi
Trovare le fonti degli aromi sgradevoli è più facile che mai con la tecnologia LECO GC-MS. Quantificare e schermare i campioni con una singola iniezione utilizzando la spettrometria di massa a tempo di volo di cromatografia gassosa bidimensionale LECO (GCxGC TOFMS).
Caratterizzano le fragranze naturali; matrice e svela oli essenziali complessi. Identificano le contaminazioni e i retrogusti al fine di migliorare la qualità e la redditività. Guarda esempi specifici con le nostre note applicative e webinar per scoprire come la tecnologia GC e GC×GC di LECO può potenziare il tuo laboratorio od ottenere informazioni dettagliate sugli strumenti LECO per l'analisi sensoriale, aromatica e delle fragranze.
Di seguito troverai un compendio di contenuti in base all’analisi dell’aroma. Per alcuni contenuti ti chiediamo gentilmente di inviare il nostro modulo. Dopo averlo compilato una volta, avrai accesso a tutti i file.
Product portfolio
PEGASUS® BT GC-TOFMS and PEGASUS® BT 4D GC×GC-TOFMS
L'affidabilità e la durata collaudate del nostro marchio Pegasus in una comoda applicazione da banco offrono più tempo di attività, dati chimici migliori e un aumento della produttività e dell'efficienza complessive.
► Eventi recenti/presentazioni on demand
► "Webinar sulle soluzioni avanzate per il flusso di lavoro GC-MS"
Scopri come strumenti all’avanguardia e soluzioni software si uniscono per migliorare le tue applicazioni di gascromatografia mono e bidimensionale (GC-MS e GC × GC-MS).
Watch the video ...
► “1° Workshop sul vino europeo LECO”
Guarda le varie presentazioni degli esperti su GC-TOF-MS/GC×GC-TOF-MS per le analisi del vino e scopri come GC-MS può migliorare le tue analisi quotidiane.
Watch the video ...
► “Sfide e soluzioni video on demand nella profilazione degli aromi (MDCW 2022)”
Ti sei perso il webinar di LECO durante l’MDCW 2022?
La presentazione di Lena M. Dubois discute le soluzioni alle sfide affrontate in ..
Watch the video ...
► “Verso cibi vegetariani ancora più gustosi”
Hans-Gerd Janssen (Unilever) ed Ed Rosing (Wageningen University) discutono dell’interpretazione dei dati GCxGC-MS non mirati per l’avanzamento ...
Watch the video ....
► “Capire i sapori sgradevoli e i cattivi odori del cibo”
L'utilizzo della gascromatografia-olfattometria (GC-O) può aiutare a identificare i composti odorosi attivi in miscele complesse. Ma cosa succede se la GC-O ..
Watch the video ...
► “Analisi degli ingredienti aromatici tramite GCMS”
Marlene Moskowitz, PhD, chimico analista presso McCormick, discute di come i loro laboratori sfruttano la gascromatografia di massa ..
Watch the video ...
Biblioteca e pubblicazioni di analisi degli aromi
Learn more about our solutions for aroma analysis and read our Application Notes. In the following, you are going to find a content compendium.
Application Notes
PEGASUS® BT GC-TOFMS
- Pairing Olfactory Detection with GC-MS to Clarify Identification of Isomers
- Characterization and Comparison of Whiskey Aroma Profiles with GC-TOFMS and Sync
- Differentiation of Baijiu Spirits
- Analysis of Citrus Essential Oils
- Comparison of Traditional Chardonnay and Buttery Chardonnay
- Sensitive Analysis of Tea Tree Essential Oil
- Brewery Process Monitoring
- Essential Oil Characterization
- Profilo dell’aroma chimico della barretta di cioccolato fondente
- Track Aging of an American IPA Beer at Different Storage Temperatures
- Monitoring of Furan Derivates and Key Aroma Species Simultaneously in Coffee and Coffee Substitutes
Application Notes
PEGASUS® BT 4D GC×GC-TOFMS
- Statistical Differentiation of Baijiu Spirits Using SPME-GC×GC-TOFMS and ChromaTOF® Tile Software
- Workflow for the Assessment of Key Aroma Compounds of Pumpernickel Bread Variations
- Comprehensive Evaluation of Scotch Whisky Aroma Profiles Using SPME-GC×GC-TOFMS
- Pesto Aroma Profile SPME
- Pesto ChromaTOF Tile SPME
- Frankincense and Myrrh: Visual Characterization and Comparison of Essential Oils
- Caratterizzazione dell'olio essenziale di Citronella
- Caratterizzazione e differenziazione del livello di torrefazione del caffè
- Differenziazione dei profili di aroma di miele
- Improved Characterization and Differentiation of Perfume Samples
- Differentiating Original-Brand and Imitation Perfumes with GCxGC-TOFMS and ChromaTOF Tile
eFoodLab Article | New Dimensions in Beverage Characterisation
In this issue, eFoodLab published an interview with Dr. Geraint (Taff) Morgan of the Applied Science & Technology Group at The Open University, UK, who discussed his team's activities as part of their impact agenda to develop and deploy novel analytical solutions for beverage products within the industry.
eFoodLab Article | Trends and Patterns in the Alcoholic Beverage Industry
eFoodLab spoke to some key players to investigate current trends and patterns of work in the sector and valuable insights were provided by "In The Welsh Wind", a distilled spirits company forging new and alternative approaches to produce authentic and sustainable Welsh Whiskey, "He Stringer Flavours", a flavour and fragrance company innovating flavour formulations to provide brands and consumers with increased choice and quality.
eFoodLab Article | Innovative Beer crafted from unsold bread
eFoodLab is talking about 'Cacciatori di Briciole' beer, exploring its aromatic intricacies through advanced gas chromatography techniques, a testament to sustainable brewing innovation.
Portafoglio degli altri strumenti
Sfoglia la nostra linea di prodotti analitici scientifici per l'analisi sensoriale, del gusto e della fragranza per trovare lo strumento appropriato per i tuoi scopi specifici.
QuadJet™ SD di LECO è la soluzione ideale per i campioni che arrivano nel vostro laboratorio. Combinando la sensibilità del rilevamento a ionizzazione di fiamma (FID) con l’aumento della risoluzione cromatografica della gascromatografia bidimensionale completa (GCxGC), QuadJet SD fornisce una misura migliore dei componenti effettivi del campione rispetto a un’analisi GC lineare. Nessun altro sistema disponibile sul mercato è in grado di offrire la stessa riduzione di rumore ed errori offerta da QuadJet SD.
Offerto esclusivamente da LECO, il nostro autocampionatore L-PAL3 offre una fiala con capacità maggiore, iniezioni GC prive di discriminazione (iniezioni ultraveloci), uno scambio automatico di strumenti per passare da un tipo di iniettore (liquido, headspace o SPME), carryover ridotto e rilevamento dei campioni minimi nelle fiale per evitare iniezioni errate.
Il modo più semplice per rendere GC×GC parte della tua analisi quotidiana
Simply GCxGC di LECO è uno strumento gratuito progettato per guidarti attraverso le fasi di creazione di un metodo GCxGC ottimizzato per i tuoi campioni complessi. Crea un metodo GCxGC da zero o converti un metodo 1D esistente in GCxGC.
Modulatore di flusso GC×GC
Il nostro innovativo modulatore di flusso FLUX GCxGC è stato progettato con un obiettivo: rendere la GCxGC più consuetudinaria, accessibile e facile da utilizzare.
La modulazione termica offre le massime prestazioni per qualsiasi modulatore disponibile per GCxGC. Gli altri tipi di modulatori termici o basati su valvole non possono competere con il modulatore GCxGC di LECO in quanto a robustezza, affidabilità e prestazioni.
Fonte di ionizzazione per la spettrometria di massa della gascromatografia
L'innovativa Multi-Mode Source™ (MMS™) sfrutta tutti i vantaggi delle tre modalità di ionizzazione più comuni: ionizzazione elettronica (EI), ionizzazione chimica positiva (PCI) e ionizzazione chimica negativa (NCI/ECNI) e le combina in un'unica fonte di facile utilizzo. Niente più cambio di hardware, niente più problemi di allineamento:
con l'MMS cambiare le modalità di ionizzazione è facile come premere un pulsante.
Sviluppato esclusivamente da LECO, ChromaTOF® è progettato unicamente per soddisfare le esigenze dei professionisti di laboratorio di oggi, elaborando e analizzando le grandi quantità di dati acquisiti con i nostri strumenti a tempo di volo.
Sviluppato esclusivamente da LECO, ChromaTOF® è progettato unicamente per soddisfare le esigenze dei professionisti di laboratorio di oggi, elaborando e analizzando le grandi quantità di dati acquisiti con i nostri strumenti a tempo di volo.
Porta la potenza della precisione della massa nei tuoi problemi di identificazione
L’Identification Grading System (IGS) di LECO facilita la revisione dei dati consentendo agli utenti di vedere, giustificare e riferire rapidamente quali sostanze chimiche sono in un particolare campione.
Let LECO help you find the right instruments for your needs.
Se desideri saperne di più sui nostri prodotti e le nostre soluzioni per l’analisi degli aromi, prenota un biglietto gratuito per la nostra fiera virtuale o pianifica una demo online per fare un’analisi più approfondita dei nostri strumenti.
Soluzioni LECO per l'analisi degli aromi
Trovare le fonti degli aromi sgradevoli è più facile che mai con la tecnologia LECO GC-MS. Quantificare e schermare i campioni con una singola iniezione utilizzando la spettrometria di massa a tempo di volo di cromatografia gassosa bidimensionale LECO (GCxGC TOFMS).
Caratterizzano le fragranze naturali; matrice e svela oli essenziali complessi. Identificano le contaminazioni e i retrogusti al fine di migliorare la qualità e la redditività. Guarda esempi specifici con le nostre note applicative e webinar per scoprire come la tecnologia GC e GC×GC di LECO può potenziare il tuo laboratorio od ottenere informazioni dettagliate sugli strumenti LECO per l'analisi sensoriale, aromatica e delle fragranze.
Di seguito troverai un compendio di contenuti in base all’analisi dell’aroma. Per alcuni contenuti ti chiediamo gentilmente di inviare il nostro modulo. Dopo averlo compilato una volta, avrai accesso a tutti i file.
Product portfolio
PEGASUS® BT GC-TOFMS and PEGASUS® BT 4D GC×GC-TOFMS
L'affidabilità e la durata collaudate del nostro marchio Pegasus in una comoda applicazione da banco offrono più tempo di attività, dati chimici migliori e un aumento della produttività e dell'efficienza complessive.
► Eventi recenti/presentazioni on demand
► "Webinar sulle soluzioni avanzate per il flusso di lavoro GC-MS"
Scopri come strumenti all’avanguardia e soluzioni software si uniscono per migliorare le tue applicazioni di gascromatografia mono e bidimensionale (GC-MS e GC × GC-MS).
Clicca qui per vedere il video.
► “1° Workshop sul vino europeo LECO”
Guarda le varie presentazioni degli esperti su GC-TOF-MS/GC×GC-TOF-MS per le analisi del vino e scopri come GC-MS può migliorare le tue analisi quotidiane.
Compila il nostro modulo per guardare il video.
► “Sfide e soluzioni video on demand nella profilazione degli aromi (MDCW 2022)”
Ti sei perso il webinar di LECO durante l’MDCW 2022?
La presentazione di Lena M. Dubois discute le soluzioni alle sfide affrontate in ..
Compila il nostro modulo per guardare il video.
► “Verso cibi vegetariani ancora più gustosi”
Hans-Gerd Janssen (Unilever) ed Ed Rosing (Wageningen University) discutono dell’interpretazione dei dati GCxGC-MS non mirati per l’avanzamento ...
Compila il nostro modulo per guardare il video.
► “Capire i sapori sgradevoli e i cattivi odori del cibo”
L'utilizzo della gascromatografia-olfattometria (GC-O) può aiutare a identificare i composti odorosi attivi in miscele complesse. Ma cosa succede se la GC-O ..
Compila il nostro modulo per guardare il video.
► “Analisi degli ingredienti aromatici tramite GCMS”
Marlene Moskowitz, PhD, chimico analista presso McCormick, discute di come i loro laboratori sfruttano la gascromatografia di massa ..
Compila il nostro modulo per guardare il video.
Biblioteca e pubblicazioni di analisi degli aromi
Learn more about our solutions for aroma analysis and read our Application Notes. In the following, you are going to find a content compendium. We kindly ask you to submit our form. Afterwards you‘ll get access to all the files.
Application Notes
PEGASUS® BT GC-TOFMS
Please complete the form to get access to all App Notes.
- Pairing Olfactory Detection with GC-MS to Clarify Identification of Isomers
- Characterization and Comparison of Whiskey Aroma Profiles with GC-TOFMS and Sync
- Differentiation of Baijiu Spirits
- Analysis of Citrus Essential Oils
- Comparison of Traditional Chardonnay and Buttery Chardonnay
- Sensitive Analysis of Tea Tree Essential Oil
- Brewery Process Monitoring
- Essential Oil Characterization
- Profilo dell’aroma chimico della barretta di cioccolato fondente
- Track Aging of an American IPA Beer at Different Storage Temperatures
- Monitoring of Furan Derivates and Key Aroma Species Simultaneously in Coffee and Coffee Substitutes
Application Notes
PEGASUS® BT 4D GC×GC-TOFMS
Please complete the form to get access to all App Notes.
- Statistical Differentiation of Baijiu Spirits Using SPME-GC×GC-TOFMS and ChromaTOF® Tile Software
- Workflow for the Assessment of Key Aroma Compounds of Pumpernickel Bread Variations
- Comprehensive Evaluation of Scotch Whisky Aroma Profiles Using SPME-GC×GC-TOFMS
- Pesto Aroma Profile SPME
- Pesto ChromaTOF Tile SPME
- Frankincense and Myrrh: Visual Characterization and Comparison of Essential Oils
- Caratterizzazione dell'olio essenziale di Citronella
- Caratterizzazione e differenziazione del livello di torrefazione del caffè
- Differenziazione dei profili di aroma di miele
- Improved Characterization and Differentiation of Perfume Samples
- Differentiating Original-Brand and Imitation Perfumes with GCxGC-TOFMS and ChromaTOF Tile
eFoodLab Article | New Dimensions in Beverage Characterisation
In this issue, eFoodLab published an interview with Dr. Geraint (Taff) Morgan of the Applied Science & Technology Group at The Open University, UK, who discussed his team's activities as part of their impact agenda to develop and deploy novel analytical solutions for beverage products within the industry.
eFoodLab Article | Trends and Patterns in the Alcoholic Beverage Industry
eFoodLab spoke to some key players to investigate current trends and patterns of work in the sector and valuable insights were provided by "In The Welsh Wind", a distilled spirits company forging new and alternative approaches to produce authentic and sustainable Welsh Whiskey, "He Stringer Flavours", a flavour and fragrance company innovating flavour formulations to provide brands and consumers with increased choice and quality.
eFoodLab Article | Innovative Beer crafted from unsold bread
eFoodLab is talking about 'Cacciatori di Briciole' beer, exploring its aromatic intricacies through advanced gas chromatography techniques, a testament to sustainable brewing innovation.
Portafoglio degli altri strumenti
Sfoglia la nostra linea di prodotti analitici scientifici per l'analisi sensoriale, del gusto e della fragranza per trovare lo strumento appropriato per i tuoi scopi specifici.
QuadJet™ SD di LECO è la soluzione ideale per i campioni che arrivano nel vostro laboratorio. Combinando la sensibilità del rilevamento a ionizzazione di fiamma (FID) con l’aumento della risoluzione cromatografica della gascromatografia bidimensionale completa (GCxGC), QuadJet SD fornisce una misura migliore dei componenti effettivi del campione rispetto a un’analisi GC lineare. Nessun altro sistema disponibile sul mercato è in grado di offrire la stessa riduzione di rumore ed errori offerta da QuadJet SD.
Offerto esclusivamente da LECO, il nostro autocampionatore L-PAL3 offre una fiala con capacità maggiore, iniezioni GC prive di discriminazione (iniezioni ultraveloci), uno scambio automatico di strumenti per passare da un tipo di iniettore (liquido, headspace o SPME), carryover ridotto e rilevamento dei campioni minimi nelle fiale per evitare iniezioni errate.
Il modo più semplice per rendere GC×GC parte della tua analisi quotidiana
Simply GCxGC di LECO è uno strumento gratuito progettato per guidarti attraverso le fasi di creazione di un metodo GCxGC ottimizzato per i tuoi campioni complessi. Crea un metodo GCxGC da zero o converti un metodo 1D esistente in GCxGC.
Modulatore di flusso GC×GC
Il nostro innovativo modulatore di flusso FLUX GCxGC è stato progettato con un obiettivo: rendere la GCxGC più consuetudinaria, accessibile e facile da utilizzare.
La modulazione termica offre le massime prestazioni per qualsiasi modulatore disponibile per GCxGC. Gli altri tipi di modulatori termici o basati su valvole non possono competere con il modulatore GCxGC di LECO in quanto a robustezza, affidabilità e prestazioni.
Fonte di ionizzazione per la spettrometria di massa della gascromatografia
L'innovativa Multi-Mode Source™ (MMS™) sfrutta tutti i vantaggi delle tre modalità di ionizzazione più comuni: ionizzazione elettronica (EI), ionizzazione chimica positiva (PCI) e ionizzazione chimica negativa (NCI/ECNI) e le combina in un'unica fonte di facile utilizzo. Niente più cambio di hardware, niente più problemi di allineamento:
con l'MMS cambiare le modalità di ionizzazione è facile come premere un pulsante.
Sviluppato esclusivamente da LECO, ChromaTOF® è progettato unicamente per soddisfare le esigenze dei professionisti di laboratorio di oggi, elaborando e analizzando le grandi quantità di dati acquisiti con i nostri strumenti a tempo di volo.
Sviluppato esclusivamente da LECO, ChromaTOF® è progettato unicamente per soddisfare le esigenze dei professionisti di laboratorio di oggi, elaborando e analizzando le grandi quantità di dati acquisiti con i nostri strumenti a tempo di volo.
Porta la potenza della precisione della massa nei tuoi problemi di identificazione
L’Identification Grading System (IGS) di LECO facilita la revisione dei dati consentendo agli utenti di vedere, giustificare e riferire rapidamente quali sostanze chimiche sono in un particolare campione.
Let LECO help you find the right instruments for your needs.
Se desideri saperne di più sui nostri prodotti e le nostre soluzioni per l’analisi degli aromi, prenota un biglietto gratuito per la nostra fiera virtuale o pianifica una demo online per fare un’analisi più approfondita dei nostri strumenti.
"I have used the LECO BT4D for the separation, identification, and quantification of anabolic steroids.
The advantages of the GC×GC system to separate stereoisomers in a complex matrix means time can be saved from doing complex sample preparation and extraction procedures. The ability to separate and quantify low levels of target analytes from high levels of matrix interferences has been key to my work. With LECO’s user-friendly ChromaTOF software, expert application scientists, and fantastic technical service team, LECO is a reliable and trusted research partner."
Mit 85 Jahren Erfahrung in der Labortechnik wissen wir inzwischen ziemlich gut, dass es nicht nur darauf ankommt, hochwertige, spezialisierte Technik anzubieten, sondern ebenso zuverlässige Lösungen, wenn es um individuelle Anforderungen wie Service, Wartung, Support und Know-How geht.
Lernen Sie unseren professionellen LECO Kundenservice kennen! Wir bieten Ihnen ein breites Leistungsportfolio und helfen Ihnen dabei, die Produktivität und Effizienz Ihres Labors zu steigern.
Überzeugen Sie sich selbst - was können wir für Sie tun?
Soluzioni LECO per MOSH/MOAH
Qualunque siano i requisiti per la preparazione del campione, sfrutta la potenza della tecnologia LECO GCxGC & TOF per risolvere le complesse sfide dell'analisi MOSH/MOAH.
Soluzioni LECO per l’analisi di energia e carburanti
Espandere, conservare e ampliare le nostre limitate risorse energetiche significa che le aziende dovranno essere in grado di analizzare nuove fonti e convalidare la qualità delle forniture esistenti. Gli strumenti LECO consentono alle aziende energetiche di conformarsi a normative EPA sempre più severe.
Pur continuando a essere leader nei test al carbonio/zolfo su carbone e carburante, LECO ha esteso le sue competenze nei biocarburanti, additivi, prodotti petroliferi e carburanti a reazione. Man mano che queste risorse diventano più preziose, la tecnologia LECO è qui per convalidarne il potenziale e la qualità, aiutandoti nel contempo a soddisfare le normative governative.
Product portfolio
Tap into the power of cutting-edge technology. Our instruments excel in characterizing even the most intricate mixtures, enabling precise determination and ultimate analysis. Gain invaluable insights for e. g. calculating material/energy balances, optimizing efficiencies, and assessing emissions potentials. Experience the pinnacle of accuracy and efficiency in energy and fuels analysis with our advanced solutions.
Sfoglia la nostra linea di prodotti analitici scientifici per l'analisi dell'energia e dei combustibili per trovare lo strumento appropriato per i tuoi scopi specifici.
SC832 zolfo e carbonio
La serie 832 di determinatori elementari LECO è specificamente progettata per eseguire analisi del carbonio e dello zolfo di carbone, carburante, lubrificanti, oli combustibili e molti altri materiali organici e alcuni inorganici. La serie 832 è una risorsa preziosa per qualsiasi laboratorio che necessita di analisi rapide e accurate sui combustibili solidi.
CHN828 Analisi elementale carbonio/idrogeno/azoto
La serie CHN828 consente di ottenere risultati rapidi in matrici organiche come cibo e carburanti. Il sistema del forno a doppio stadio funziona a temperature fino a 1.050 °C con un ambiente di ossigeno esclusivo che garantisce la combustione completa di tutti i campioni organici, senza richiedere ulteriori reagenti ossidanti metallici o altri gas di trasporto. La capacità di massa del campione macro abbinata a tempi di ciclo di 4 minuti rendono la serie CHN828 perfetta per una gamma di applicazioni diverse, offrendo allo stesso tempo una portata senza precedenti.
TGA8O1 Umidità / Cenere / Materia volatile
Il TGA801 è la soluzione completa per un'analisi macro termogravimetrica rapida e robusta dei costituenti. Determina la perdita di peso come umidità totale, ceneri, contenuto volatile o LOI in vari materiali organici, inorganici e sintetici. Il TGA801 è perfetto per una varietà di industrie e applicazioni, inclusi mangimi, prodotti della macinazione, alimenti, catalizzatori, carbone/carburante e cemento.
AC600 Calorimetria semiautomatica
L'AC600 è un calorimetro lsoperibol che fornisce risultati calorici rapidi e accurati per vari materiali organici come carbone, carburante, oli combustibili e materiali di scarto. Il suo design unico combina la tecnologia hardware e software all'avanguardia con l'automazione e le caratteristiche ergonomiche per migliorare le prestazioni e la portata.
PEGASUS® BT GC-TOFMS
L'affidabilità e la durata collaudate del nostro marchio Pegasus in una comoda applicazione da banco offrono più tempo di attività, dati chimici migliori e un aumento della produttività e dell'efficienza complessive.
PEGASUS® BT 4D GC×GC-TOFMS
L'affidabilità e la durata collaudate del nostro marchio Pegasus in una comoda applicazione da banco offrono più tempo di attività, dati chimici migliori e un aumento della produttività e dell'efficienza complessive.
QuadJet™ SD
QuadJet™ SD di LECO è la soluzione ideale per i campioni che arrivano nel vostro laboratorio. Combinando la sensibilità del rilevamento a ionizzazione di fiamma (FID) con l’aumento della risoluzione cromatografica della gascromatografia bidimensionale completa (GCxGC), QuadJet SD fornisce una misura migliore dei componenti effettivi del campione rispetto a un’analisi GC lineare. Nessun altro sistema disponibile sul mercato è in grado di offrire la stessa riduzione di rumore ed errori offerta da QuadJet SD.
PEGASUS® GC-HRT+ (alta risoluzione TOFMS)
La tecnologia TOFMS ad alta risoluzione offre funzionalità MS ad alte prestazioni, tra cui velocità di acquisizione, precisione di massa, abbondanza isotopica relativa accurata, risoluzione di massa e gamma dinamica, tutte disponibili contemporaneamente. Progettato per il laboratorio di ricerca e sviluppo per approfondire campioni di prodotti petrolchimici e risolvere matrici complesse.
PEGASUS® GC-HRT+ 4D
Pegasus GC-HRT+ 4D di LECO offre agli utenti la capacità senza precedenti di studiare i campioni di petrolio più complessi e identificare analiti sconosciuti. Trova più analiti che mai utilizzando High Resolution Deconvolution® (HRD® (Deconvoluzione ad alta risoluzione)) e la completa cromatografia GC—GC.
Energy & Fuels Publication Library
Explore the depths of energy and fuels analysis with LECO. Dive into our informative eBook and discover a wealth of Application Notes covering mass spectrometry, thermal analysis, and elemental analysis in the field of energy and fuels. Gain valuable insights by filling out our form to access and download the eBook today.
eBook Applicazioni di energia e combustibili
eBook interattivo per applicazioni di energia e combustibili
LECO Europe B.V.
Please complete our form to download the eBook ...
Brochure LECO Solutions for Energy & Fuels Analysis"
LECO Brochure in A4 format for the “Energy & Fuels” market
LECO Europe B.V.
Please download the Brochure ...
If you want to learn more about our products and solutions for energy & fuels analysis, book a free ticket to our Virtual Trade Show, or schedule an online demo for a deeper insight in our instruments.
Le microplastiche sono onnipresenti nel mondo, dalla neve artica al ghiaccio antartico e ovunque nel mezzo. Ci sono trilioni di particelle di microplastica che galleggiano sulla superficie dell’acqua e si stima che tutti, dai neonati agli adulti, ne ingeriscano da dozzine a decine di migliaia ogni giorno.
Ora disponibile come video on-demand!
Guarda l'analizzatore MOSH / MOAH avanzato di LECO in azione!
Il primo spettrometro di massa a tempo di volo (TOF, Time-of-Flight) è stato proposto nel 1946 e da allora il design è stato perfezionato e ripetuto.
Con un intervallo di massa illimitato visibile in ogni spettro e un'elevata velocità di generazione spettrale sono stati immediatamente chiari i vantaggi della spettrometria di massa TOF. Sebbene siano migliorati gli strumenti, alla fine hanno incontrato limitazioni fisiche che ne hanno limitato il potere di risoluzione. Bisognava lavorare di più.
All the tricks of the trade won't be enough if your instruments can't handle the speed. LECO's Pegasus® line is designed to take full advantage of the speed of TOFMS analyses without sacrificing the sensitivity you need, and our StayClean® Ion Source means you never have to slow down to clean out your engine.
Aberystwyth University
"We originally expected to purchase a quadrupole instrument so buying a TOF was a little unexpected but definitely worth it as the data is far richer than what a quadrupole would have supplied. In the three years we have had the instrument running metabolomic matrixes the source has never been cleaned and the data is still superb and consistent. We love our Pegasus BT, it does a fab job of running my FAME samples including milk, yogurt, kefir, biltong and bacteria."
CNAP | University of York
"Our metabolomics research has utilised a LECO Pegasus 4D for over 15 years. Total downtime has probably been less than 20 days for the entire 15 years. When we do have a problem or even a question about using the instrument, LECO are very swift to respond, resolve the issue and offer support and assistance usually within a day of contacting them, and quite often on the same day. The source has never been cleaned or replaced, and we still have the same detector from the original installation. Multiple papers have been produced using data produced from our LECO and I can honestly say it’s been a great asset to our team at York University."
University of Southampton
"In 2019 EPSRC funded our vision for a regional Centre of Excellence (CoE) in 2 dimensional gas chromatography and mass spectrometry. This Regional CoE, initially embracing the Universities of Bath, Portsmouth, Southampton, and Swansea, will significantly drive discovery, characterisation and quantification of new modalities, delivering a step change in capability for detection and identification of new species that cannot be separated and determined by 1D GC alone.
LECO’s Pegasus HRT 4D GC×GC-TOFMS and the benchtop BT4D GC×GC-TOFMS, both with extensive automated sample handling capability were delivered in late 2019 and early 2020. Installation of these state-of-the-art instruments was complicated by Covid-19 and lockdown 1.0. With such complex instrumentation, and application areas, effective training was key; here LECO took the initiative and provided both bespoke local and on-demand online training.
The level of service support and close collaborative relationship with LECO (applications team and account manager) has been first rate. Both systems can now be operated remotely, enabling high level users from across the South West region to access the instrumentation and allow many complex questions to be probed. Our work covers a vast array of application, e.g. petrochemical, environmental and metabolomics. The data sets are rich and complex, yet simplified by a user friendly software interface. Compared to 1D-GC, the 4D systems provide an astonishing number of additional analyte identifications, giving us deeper insight and understanding of the samples. Combining LECO’s high resolution mass spectrometry with comprehensive gas chromatography, multiple sample handling options such as SPME, Pyrolysis and TD along with full automation has created a world class laboratory of which we are all very proud."
Sono disponibili le presentazioni seguenti:
Presentazione LECO a EURO Fed Lipid 2021
Lingua inglese
- "18° EURO Congresso ed Expo Euro Fed Lipid, 21 ottobre 2021"
Fondamenti sull’analisi MOSH/MOAH completa
Lingua inglese
- "Fundamentals on LC-GC Coupling" di Dr. Andreas Bruchmann | Axel Semrau GmbH & Co KG
- "Principles and Instrumentation of GC×GC and ToF-MS" di Prof. Dr. Ir. Hans-Gerd Janssen | University of Wageningen & Unilever
- "LC–GC×GC–ToF-MS/FID: Una potente piattaforma per la determinazione MOSH&MOAH” della Prof.ssa Giorgia Purcaro | University of Liège
Lingua spagnola
- "Cromatografía Bidimensional Exhaustiva acoplada a Espectrometría de Masas de Tiempo de Vuelo: Características y viabilidad para el control y análisis alimentario" by Lourdes Ramos | CSIC- IQOG
- "Contaminación MOSH / MOAH. Verificación mediante GC×GC-TOF-MS" di Silvia Losa | SGS Berlín
Le nostre ultime presentazioni online per l'analisi MOSH/MOAH sono ora disponibili come sessione su richiesta. Grazie a questi principi fondamentali imparerai tutti i pro e i contro sull’accoppiamento LC-GC, GC×GC e sul tempo di volo MS per essere in grado di determinare MOSH e MOAH nei prodotti alimentari.
Soluzioni LECO per MOSH/MOAH
Qualunque siano i requisiti per la preparazione del campione, sfrutta la potenza della tecnologia LECO GCxGC & TOF per risolvere le complesse sfide dell'analisi MOSH/MOAH.
With these fundamentals you will learn all the ins and outs on the LC–GC coupling, GC×GC and Time-of-Flight MS to able to determine MOSH and MOAH in food products. Please register for our presentations.
The Multidimensional Chromatography Workshop draws experts in this exciting field to share and discuss their research. The informal workshop also provides an excellent opportunity for those interested in multidimensional chromatography to learn more about this unique analytical technique. Research topics include advancements in multidimensional chromatography technology and applications of this highly selective chromatographic approach.
The past year with the rise of Covid-19 around the Earth has been a challenge to all of us. See how our European subsidiaries dealt with the pandemic around Europe and how our customer support and other services adapted to these new situations in the different countries. Click on the countries to see our personal experiences!
If you need any further information about how LECO operates during the Corona pandemic or to schedule your personal appointment with us, click on the contact button.
The start of the years begins with the usual enthusiasm, targets set, goals to achieve and strategy to achieve them. I remember being in Dusseldorf for a managers meeting on March the 3rd. Life was still normal, and the word ’lockdown’ was only ever heard on a Friday when my children were watching Wrestling. We were able to travel, visit restaurants and have a beer without the constraints of the facemasks, social distancing and track and trace apps. Life was normal. Within a month the world changed – lockdowns, stay-at-home, work from home, stay safe.
As the LECO customers adapted to this new way of life due to COVID, so did we. Our sales force worked from home and like never before used this relatively unheard-of platform called Microsoft TEAMS to interact with customers.
“I hear the chimes of ‘TEAMS’
calling me in my sleep now.”
Our service team continued to work throughout the pandemic with the new additions to their LECO uniform. LECO face masks and gloves. And of course, let’s not forget the bottles of hand sanitiser. As well as remote selling was used, remote service support came to the forefront. Both sales and service teams adapted to continue the high level of support that has become a custom with LECO.
LECO UK has been able to adapt and continued to support our customers while keeping ourselves and customers safe. Let hope moving into 2021 we can get back to some sort of previous normality. The vaccines are coming and there is a glimmer of light at the end of the tunnel but for the moment we continue with the slogan of Hands – Face – Space.
Michael Reaney, UK Sales Director, LECO Instruments UK Ltd.
The first picture shows our engineer Yuri Laptev during a Pegasus 4D service visit to Skolkovo Institute of Science and Technology.
The second one was taken at the Analytika exhibition in Moscow last year.
Gulnara Shaidullina, Ph.D., Separation Science Sales Engineer, LECO Russia and CIS
It has for sure been a challenge even though Sweden have had less restrictions. When crossing borders to Norway, Denmark and Finland our service technicians have sometimes had to take Covid-19 tests before. We have been fortunate, no one in our team have been infected as we know of. We haven’t even been to Iceland since the start of the pandemic. Our service technicians try to go by their own cars to customers, which have meant drives up to 14 hours single way.
On the sales side it has of course been a challenge in other ways. But with ‘Teams’, online demos and Virtual Trade show our sales team have connected with our customers in the best way possible. We only attended one real trade show since the start of the pandemic – LabDays in Copenhagen – but the attendance was of course quite thin…
Lennart Schwartz, Ph.D, Sales Director Nordic Region, LECO Nordic AB
Since 14th of March of 2020, and the declaration of State of alarm in Spain, Leco Instrumentos started to work in a new different way, adapting to the new scenario of pandemic. All the employees completed a training course regarding the new risk at work and the personal protective equipment for COVID-19:
- We all learnt about the use of face masks and the way to wash our hands
- Some employees customised their masks… thanks to their mother’s support!
- Remote working was the only option in most of cases.
- Virtual meetings have come to stay.
- The service team has been active since the first day, working in safe conditions.
So far, everything was normal… But LECO Spain had to face a new challenge – to move to a new office. It was a hard task cleaning the old facilities and open boxes – a lot of boxes. And in times of COVID we had to consider to organise small groups at the office working together. Minimising risks was a priority despite of the fact that we needed to be operative in the new facility in a short time. The collaboration of the Tres Cantos-based employees was essential.
But the result made the effort worthwhile! And the Spanish LECO team is ready for 2021!
Leticia García, Commercial Director, Spain & Portugal
From the perspective of the German Service Centre, a Corona routine has emerged throughout the past months. Customer demands increased - ever so often our service engineers are only allowed to enter labs after presenting a negative Corona test result. Of course, this requires special logistics in scheduling. In addition, there are different Corona rules the federal states of Germany and abroad, which makes planning much more difficult. But our colleagues adapt, as the pictures show, and as our colleague Manuel Lindemann describes below.
"When the pandemic really took off from March / April 2020, I first noticed a lot of uncertainty among both myself and the customers. There were many questions: What is Corona? What happens if I fall ill? How will this affect my work? Will the customers still let me enter their lab? How will LECO react? Now, almost a year later, there are still some questions left to be answered, but as humans we adapt and get used to the new circumstances – positive and negative.
in the beginning of the pandemic, I remember waiting for hours in 100m-long queues between lorry drivers and other visitors at a company and having to wait for the gatekeeper to let me pass. And there were customers who had their "special" views. From "Corona doesn't exist” to “You don't need the mask here" and "We have an internal lockdown, you can't get in" – it was all there.
After one year many questions remain unanswered, but some questions have already become obsolete. What remained as well, unfortunately, are the waiting times at customers‘ sites. Simply walking in and working on a unit is no longer possible. "Where are you from? Have you had contact with infected people? What does your Corona Warn app say? Do you have any symptoms?” ...And so on. What I've also noticed is that social interaction often gets left behind these days unfortunately – be it a casual conversation or just a gesture that disappears behind the mask. But, hopefully that is to come back soon.
But LECO protect their employees very well and always has an open ear for questions – a solution will be found together. All in all, I think we have organised ourselves very well and will probably make it through the rest of the pandemic."
Manuel Lindemann & Thomas Post, LECO Instrumente GmbH Deutschland
After a beginning of year full of prospects and projects, the arrival of Covid-19 took us by surprise. Italy was the first European nation to be massively attacked by the virus, the first cases recorded were in the north of the country, particularly in Lombardy, the region where the headquarters of the LECO branch in Italy are located.
To counter the spread of the virus, the entire country was placed in the "red zone" and operations were greatly reduced to adapt to the new situation.
- The symposium of world interest on the GC×GC in Riva del Garda, as well as other local events, albeit no less important, have been cancelled
- We did our meetings online
- The office staff worked in smart working
- The technical staff continued to follow their customers both remotely via the telephone and with remote interventions, and in person with the help of masks, gloves, overalls and protective goggles.
The pandemic has led us to cover our faces with masks, but it has not managed to extinguish our enthusiasm and we hope that 2021, together with the vaccine, gives us the opportunity to resume showing our smiles.
Rita M. Monfredini, LECO Italy S.R.L.
We’re dealing with the pandemic problem in a similar way, like the rest of the world:
- Using, masks and gloves
- Struggling with scheduling sales visits
- Mostly using ‘Teams’ and mobile phones to contact with each other and with customers…
Tomasz Stójkowski, Sales Director LECO Poland & Baltics
Europe
Online Demo Service at European Application & Technology Center Berlin
Since February 2020 we provide an Online Demo Service at our European Application & Technology Center in Berlin, giving customers an insight into our LECO products and laboratory processes conveniently from their desks and without the need to travel. For our Online Demo Service, a good preparation is required to meet our's and our customers’ high standards.
Preparation
- The sales enigneer requests instrument, possible date, and time at the EATC
- After feedback, the date and time is clarified with the customer
- After completion of our internal Event Request Form to collect all needed information about the customer, instrument, date and time the EATC blocks the date for the customer
- The team at EATC provides an online meeting link accordingly and invites the sales engineer to this meeting
- The sales engineer then provides the invitation with this link to their customer and if needed other colleagues who will participate.
Demo Day
- Customer and sales engineer login to the online meeting which will be started by the EATC team.
- The camera at EATC is usually placed in front of the desired instrument, when the meeting starts.
- The sales engineer starts with an introduction of themselves and the EATC team in local language.
- This is followed by some introductory words to outline the demo – also in local language
- The EATC team can do measurements of standards, explain the analysis, and point and zoom the camera wherever needed to get the best possible instrument and software overview.
- It is also possible to measure customer samples, if they are provided some days in advance to the online demo.
Get in touch with us to arrange an individual online appointment for you!
Visit our LECO Virtual Trade Show
Due to the Corona pandemic, numerous trade shows and events are being cancelled or postponed where we would have liked to welcome or customers as a guest. To give you the opportunity to stay in touch with LECO, we have organised our LECO Virtual Trade Show. Our specialists invite you to get to know our solutions for various application fields and markets in a personal meeting.
Visit our registration website and book your free ticket today. Your local sales partner will schedule a meeting and guide you through our exhibition and introduce you to our solutions for your lab.
GET YOUR FREE TICKET
È di nuovo quel periodo dell’anno in cui le canzoni delle feste vengono trasmesse alla radio 24 ore su 24, 7 giorni su 7 e la gente inizia a chiedersi cosa siano, esattamente, l’incenso e la mirra e perché siano regali tanto preziosi. LECO ha inserito questi due oli nel Pegasus BT 4D per scoprirne le differenze.
L’incenso (dall’albero della boswellia) e la mirra (dall’albero della commifora) sono entrambe resine che sono comunemente usate come profumi e incenso e lo sono state per migliaia di anni. Gli oli essenziali estratti da queste resine possono essere analizzati utilizzando la gascromatografia, ed è esattamente ciò che hanno fatto gli scienziati di LECO.
Estendendo l’analisi a una seconda dimensione utilizzando l’analisi GC×GC di Pegasus BT 4D, ancora più informazioni possono essere raccolte dai campioni estratti da queste sostanze. L’analisi GC×GC produce anche intrinsecamente cromatogrammi strutturati in cui analiti chimicamente simili tendono a eluire in bande ordinate attraverso lo spazio di separazione GC×GC. Ciò fornisce il contesto per l’identificazione e consente una rapida caratterizzazione visiva delle classi di composti.
For a more detailed breakdown of the analysis of these oils and how the GC×GC separation provides a huge advantage in the characterisation and comparison of these samples, fill in the form and check out our application note.
Guarda il webinar di LECO in collaborazione con The Analytical Scientist ora disponibile per la visualizzazione su richiesta. Il webinar presenta “GC × GC-HR-TOFMS per uno screening non mirato di Breathomics” di Pierre-Hugues Stefanuto, Lead Scientist presso l’Università di Liegi
Il tuo Pegasus® BT è uno strumento potente, ma se non sei sicuro di come utilizzare alcune delle sue funzioni, non potrai trarre il massimo vantaggio dal tuo investimento. LECO sta lanciando LECOLearn, un sito di formazione online su richiesta per aiutarti a massimizzare le prestazioni del tuo laboratorio.
La metabolomica rappresenta una sfida sia per i metodi analitici utilizzati, che per la riduzione dei dati necessaria all'interpretaizone dei risultati. Nessuna tecnica analitica singola può essere utilizzata per la caratterizzazione completa del metaboloma, e nessun metaboloma è stato completamente caratterizzato. Tuttavia la GC-MS fornisce un metodo consolidato per analizzare il metaboloma primario, mentre la LC indaga sui metaboliti secondari e terziari.
L’ascesa dell’omica è stato un tema caldo nel nostro gruppo negli ultimi anni, in parte perché la nostra esperienza si allinea in qualche modo con le esigenze di questi campi. La metabolomica è quindi particolarmente impegnativa per la comunità della scienza della separazione, che richiede l’applicazione di iterazioni di fascia alta di varie tecniche, tra cui LC, GC, MS e NMR. In effetti, quando si parla di metabolomica, la maggior parte degli strumenti analitici ha un “posto al tavolo della tecnica”, dopotutto, la multimodalità è l’unico modo per dare un senso a una complessità del campione così elevata.
Un articolo di Pierre-Hugues Stefanuto, Delphine Zanella e Jean-François Focant
Quanto è efficiente il tuo lavoro quando si tratta di campioni alimentari? Sei certo di vedere tutto ciò che il tuo campione ha da offrire? Scopri come LECO ha ampliato il possibile per quanto concerne l'analisi di sicurezza alimentare con questa serie gratuita di Webinar
LECO hosted the LA2PC // Analytical Applications Poster Competition with the aim of improving our understanding and knowledge of LECO users’ work and research. This was a great opportunity to learn more from our users and introduce their work with LECO instruments to a wider base. LECO is proud that so many excellent posters were submitted. All entries are displayed in our poster gallery.
Il Dr Ralf Löscher, Vicepresidente LECO Europe, parla con Thomas Gröger e con il Dr Jürgen Schnelle-Kreis dell’Helmholtz Zentrum München, il Centro di ricerca tedesco per la salute ambientale, per conoscere l’impatto degli aerosol sulla nostra vita quotidiana e sulla nostra salute e per ottenere alcune informazioni di base sul loro lavoro.
Siamo orgogliosi di annunciare di avere consegnato ed installato con successo un apparato unico, dedicato ad un cliente unico. Il NOFER INSTITUTE OF OCCUPATIONAL MEDICINE di Łódź, che comprende il dipartimento di monitoraggio biologico ed ambientale, guidato dal Prof. Dr. hab. n. med. Wojciech Wąsowicz, un centro fiorente di formazione, che partecipa a molti programmi nazionali ed internazionali.
Quanto è efficiente il tuo lavoro quando si tratta di campioni alimentari? Sei certo di vedere tutto ciò che il tuo campione ha da offrire? Scopri come LECO ha ampliato il possibile per quanto concerne l'analisi di sicurezza alimentare con questa serie gratuita di Webinar
Tutti i nostri Webinar hanno una durata di circa 30 minuti con una sessione conclusiva di Domande&Risposte Registrati a tutto ciò che ti interessa!
In alternativa visita la nostra nuova Fiera virtuale
Unisciti a noi per due seminari online imminenti su SepScience.com. Spieghiamo come le tecnologie LECO GC-TOF-MS e GC×GC-TOF-MS all’avanguardia possono migliorare notevolmente le tue applicazioni per l’analisi degli alimenti (9 giugno) e ambientale (11 giugno).
Fai clic per registrarti ora!
Oggi, 20 maggio, è la giornata mondiale delle api. L’ape da miele è una specie impollinatrice importante che contribuisce all’economia degli Stati Uniti con una stima di circa 15 miliardi di dollari USA all’anno attraverso l’impollinazione delle colture e 690 milioni di sterline per l’economia del Regno Unito. Le api da miele sono anche impollinatrici selvatiche importanti e svolgono un ruolo chiave nel mantenimento della biodiversità e di molti ecosistemi.
Al seminario e simposio GC×GC di LECO (filmato presso il Centro europeo di applicazione e formazione LECO di Berlino in Germania) Paul Harvath ha tenuto un discorso dal titolo “Evaluation of Oxidized Base Oils by Flow Modulated Two-Dimensional Gas Chromatography – Time of Flight Mass Spectrometry” (Valutazione degli oli base ossidati mediante cromatografia a gas bidimensionale modulata a flusso - spettrometria di massa a tempo di volo). Nel suo discorso ha fornito uno spaccato della storia e del futuro degli oli motore per auto e ha spiegato come i lubrificanti sono cambiati nel corso del tempo.
Department of Pharmacy, University of Naples Federico II
"I have been using a GC-TOFMS Pegasus BT since gennaio 2018 for Metabolomics projects. I have mainly analysed murine tissues extracts, and, I'm very happy about its robustness and high sensitivity."
UMR QualiSud, University of Avignon, France
"I use a LECO mass spectrometer for plant metabolomics ; it is an efficient machine with a very low detection limit and the Chromatof deconvolution algorithm allows to find hundreds of compounds in complex extracts."
Faculty of Forestry and Wood Sciences, Czech University of Life Sciences Prague, Czech Republic
"I have been working with LECO instruments for approx. ten years. I worked with the PEGASUS® 4D, TruTOF, GC-HRT and, for few days in Berlin, with the Pegasus BT and BT 4D – I really enjoyed that. There are several reasons why I like working with the devices and why I would not consider using other GC-MS insturments.
- LECO instruments are reliable and robust with well working peak find and mass spectral deconvolution algorithms.
- In principle, LECO instruments are allowing both target and non target analysis which can be performed in one run, with nice sensitivity.
- Data processing is easy and everything is done in one SW – no need to use complicated combinations of SWs.
- LECO has an excellent customers support"
Wolfson Atmospheric Chemistry Laboratories, University of York
"Following years of service from the old LECO PEGASUS® 4D TOF GC-MS, we upgraded to a new LECO Pegasus BT4D TOF GC-MS. The decision was made due to the exceptional separating power afforded by thecryogenic modulation and the durability of the LECO StayClean® sourcetechnology which has been carried into the updated system. The combination of the two open up a wide variety of analyses to us whichenable use of this instrument in many aspects of our research."
National Centre for AtmosphericScience (NCAS), University of York
"We send instruments into the harshest of environments and run very demanding samples on them. Bearing this in mind, our decision to upgrade the GC-MS at our remote Cape-Verde site to the new LECO PEGASUS® BT was driven by the promise of the StayClean® source. This minimizes down time and eliminates operations which are difficult to carry out when working with remote systems. The increased sensitivity of theinstrument enables us to take smaller sample volumes which again assists with easing the burden placedon the analytical machine. Finally! the upgrade from quadrupole to time of flight mass spec will enable us to keep historical datasets which can be interrogated for any compounds which prove interesting in the future."
Department of Civil Engineering University of Strathclyde
"In 2013, I became responsible for overseeing the department’s analytical suite which included a LECO PEGASUS® 4D GC×GC TOF MS as our flagshipinstrument. I had no experience in gas chromatography and found even a standard GCMS daunting. Over the past years, I received extensive support from LECO. Especially withsupport from LECO UK the instrument is still running strong a decade after purchase. I anticipate it will go for another decade and then some."
ALS Enviromental, United Kingdom
"I believe this technology and methodology will profoundly change water analysis realising major benefits for both laboratories and their customers."
SGS Institut Fresenius GmbH Berlin, Germany
"We at SGS MOSH/MOAH group are using the GC × GC-TOFMS from LECO to separate the highly complex fractions of MOSH/MOAH contaminates in food. When you want to identify special patterns of contamination species amongst other analytics (e. g carotenoids) you need a high separation power in combination with a fast screening MS. This is provided by the LECO TOF. Actually we have a new project together with LECO and another company to quantify MOSH/MOAH fractions. The complexity of the instrumentation is high, but with the support of the application team from LECO we reach our goals."
Environment Reference Lab, APA – Agência Portuguesa do Ambiente
"Initially we had some fears about whether the option of the time of flight detector would be the best for our laboratory, since we have no other system of this kind installed. However, at the end of 6 months of operation with the GC-TOFMS system, it was widely recognized internally that we made the right choice. An easy-to-operate system with high sensitivity, reproducibility and severalanalysis options for a large universe of analytes, and in the most varied matrices increases the versatility of laboratory operation as well as the possibility of responding to the most demanding customer requests."
Centre for Molecular and Cell Technologies, Saint Petersburg State University Research Park
- Analytical Phytochemistry Laboratory // Komarov Botanical Institute
- Department of Plant Physiology and Biochemistry // Saint Petersburg State University
- Department of Plant Biochemistry and Molecular Biology // Vavilov Research Institute of Plant Industry
"Our virtual metabolomics research center has six GC-MS instruments, and the LECO PEGASUS® 4D is the crown jewel of our science park. The results of GC-MS profiling performed using GC×GC technologies has madea strong impression on users and has seriously improved the quality of ourpublications. The fast-scanning capabilities of the TOF-analyzer effectively augment the dataobtained on the ordinary quadrupole, especially when working with the most complexmatrices which are most often the subject of metabolomics analysis. The reliability of the device is especially deserving of praise. The equipment can withstand a very demanding load with constant, round-the-clock operation."
Università degli Studi del Piemonte Orientale, Italy
"With the Pegasus BT 4D performing untargeted analysis today is very easy, thanks to the high sensitivity of the instrument, we are able to mine and analyze any type of sample! A combination of very good sensitivity, quality to price ratio and high flexibility make the Pegasus BT 4D system perfect for analysis of every sample"
University of Naples, Italy
"Pegasus BT is the perfect choice for identifying well-known metabolites at low concentration level in our sample, and also discovering new compounds. The most surprising advantage of the BT system is the ion source robustness! We usually work with dirty and complex samples, but we have never observed drop of sensitivity during our analyses.This reduces the time and cost of our analyses!"
TURKU Metabolomics Facility, Finland
"We use the LECO Pegasus BT instrument for the quantification of small polar metabolites. We developed a hybrid method where we quantitate 51 metabolites with standard curves and screen for any other small polar metabolites in a wide range of biological samples. This assay has a great dynamic range thanks to the sensitivity of the BT. The StayClean® ion source allows us to run hundreds of samples in a batch and be confident that the ion source will remain clean even with dirty samples such as plasma."
Czech Academy of Science, Tschechische Republik
"Compared to GC equipped with a single column, the Pegasus 4D enabled me to separate unbelievable number of analytes! Tens of thousands of separated peaks in one run was not an exception. But where the separation was not perfect, ChromaTOF software and its deconvolution algorithm did the job. Such excellent ‘separating power’ helped me discover new types of plant PCB metabolites."
Helmholtz Zentrum München (HMGU) Department “Comprehensive Molecular Analytics“, Germany
"This combination of ultrahigh chromatographic separation with high mass resolution might be still unique for a commercial available end user system."
Il nostro nuovo e-book sintetizza gran parte del lavoro applicativo di LECO nel campo della sperimentazione alimentare. Oltre al Compendio sull’applicazione l’e-book include un’introduzione alla tecnologia GC×GC e TOFMS, seguita da una panoramica delle diverse soluzioni hardware e software utilizzate per le applicazioni di analisi degli alimenti. Una bibliografia con riferimenti aggiuntivi è disponibile nell’appendice.
L’e-book è scaricabile subito da Scienza della separazione.
Scarica l’e-book qui…
NUOVO servizio demo online presso il nostro European Application and Technology Center di Berlino
Ora possiamo presentare ONLINE i nostri strumenti e soluzioni applicative, permettendoti di ottenere informazioni su come i prodotti LECO potrebbero migliorare i processi e i risultati del tuo laboratorio!
Visitaci comodamente dalla tua scrivania e senza la necessità di viaggiare. Il nostro nuovo SERVIZIO DEMO ONLINE ti consente di vedere le presentazioni dei prodotti e di ricevere consigli e suggerimenti dai nostri esperti.
Vuoi sapere come possiamo essere di aiuto nelle tue analisi dei campioni?
Faccelo sapere e possiamo organizzare una demo!
Contatta il tuo team di vendita locale per un appuntamento online individuale.
Mentre le leggi e i regolamenti cambiano, la cannabis e tutti i relativi composti chimici di interesse si presentano in un’ampia varietà di prodotti di consumo. Gli strumenti LECO, che combinano tecnologie potenti di spettrometria di massa a tempo di volo (TOF-MS) e tecnologie complete di gascromatografia bidimensionale (GC×GC), possono rendere le tue analisi più efficienti. Scopri qui come risparmiare tempo e denaro quantificando e identificando sia il terpene sia i cannabinoidi in una sola iniezione. La stessa iniezione può rivelare persino la presenza di pesticidi e altro!
Come possiamo farlo? L’uso di GC×GC aumenta drasticamente la separazione degli analiti, che insieme agli spettri di alta gamma a massa totale ottenuti da TOF-MS, consente un’individuazione di analiti di deconvoluzione potenti mediante ChromaTOF.
Se vuoi saperne di più sulla “Determinazione dei profili terpenici delle varietà di cannabis”, guarda la presentazione di Joe Binkley, direttore delle Applicazioni della Scienza della separazione.
Al GC×GC Workshop & Symposium di LECO, la Dottoressa Diane Turner ha parlato di "Selettività: dove, quando e come usarla“. Il discorso tratta le tecniche per l’analisi dei campioni, la selettività nella scelta della impostazione tecnica giusta (scelta delle colonne, parametri di ingresso, ecc.), nonché l’ottimizzazione dell’analisi dei dati.
Incontro della London Metabolomics Network e della South East Region Analytical Division della Royal Society of Chemistry a Burlington House, Londra
Alan Griffiths parla della tecnica top di gamma per la separazione GC×GC fornita da LECO. Il video è stato registrato durante l'incontro della London Metabolomics Network e della South East Region Analytical Division della Royal Society of Chemistry alla Burlington House di Londra. Il video verrà caricato su SepScience.com per la nostra recente campagna di PEGASUS®.
I fuochi d'artificio sono un punto fermo delle celebrazioni del Giorno dell'Indipendenza dell'America. Si stima che ogni anno negli Stati Uniti avvengano 16.000 spettacoli pirotecnici e che i consumatori americani spendano oltre 1 miliardo di USD in vendite di fuochi d'artificio per celebrare la festa! Oltre a un grande botto e a luci intense, in che modo questi fuochi d'artificio influenzano l’ambiente che li circonda? La sede mondiale di LECO si trova a Saint Joseph, nel Michigan, una cittadina balneare sul lago Michigan dove i fuochi d'artificio fanno da sfondo alla celebrazione del 4 luglio. L'estate scorsa, il nostro laboratorio applicativo ha pensato che sarebbe stato un esperimento utile e interessante testare l'acqua che circonda il punto di lancio dei fuochi d'artificio per esplorare gli eventuali impatti ambientali a breve termine. L'afflusso di turisti sulle spiagge del Lago Michigan durante le vacanze contribuirà sicuramente all’inquinamento dell'acqua con prodotti chimici per la cura personale (protezione solare e repellente per insetti). La valutazione di questi potenziali contaminanti in occasione delle festa del 4 luglio era l'obiettivo di questo studio.
L'analisi è stata condotta prelevando campioni d'acqua da tre diversi punti lungo la costa, considerando il sito di lancio dei fuochi d'artificio al largo del molo nonché due spiagge locali vicino al sito di lancio. Ciò è stato fatto il 2 luglio e il 4 luglio (un'ora dopo lo spettacolo pirotecnico) per fornire una misurazione accurata. Per analizzare i campioni d’acqua è stato utilizzato il sistema Pegasus HRT + 4D, offrendo una gascromatografia bidimensionale completa accoppiata alla spettrometria di massa a tempo di volo ad alta risoluzione (GC × GC-HRTOFMS). GC×GC-HRTOFMS si è rivelato un potente strumento di esplorazione in quanto ha fornito un'analisi completa non mirata dei campioni d'acqua prima e dopo lo spettacolo pirotecnico, dimostrando chiaramente le differenze chimiche tra i due. GC×GC-HRTOFMS è stato anche in grado di individuare i contributi all'inquinamento ambientale causato da questi spettacoli pirotecnici e dall'aumento del traffico umano vicino ai siti di campionamento delle acque.
Cosa è successo alla qualità dell'acqua del lago Michigan con l'aumento del turismo e dei fuochi d'artificio? I risultati potrebbero sorprenderti…
Analisi non mirate, scienza dei dati e innovazione si sono sincronizzate per sostenere l'analisi della scienza della separazione di nuova generazione nella spettrometria di massa. Lo spiega Alan Griffiths, specialista dei prodotti della scienza della separazione di LECO nel Regno Unito.
“Le idee spesso nascono l’una dall’altra e si verificano reazioni a catena. Come per le reazioni chimiche, le idee possono rimanere confinate in aree relativamente piccole prima di diffondersi gradualmente verso l'esterno. La Silicon Valley in California è un punto focale per la tecnologia. Per la spettrometria di massa (MS), la città britannica di Manchester è un punto focale. Manchester è il luogo in cui è stato prodotto il primo spettrometro di massa commerciale costruito al di fuori degli Stati Uniti…“
Leggi l'articolo completo qui…
Il mondo della chimica // Numero 12/2019 // Articolo di Alan Griffiths
Ralf Löscher parla delle ultime tecnologie e della pluriennale esperienza di LECO nel campo della strumentazione TOFMS. Il focus speciale di questa intervista si riferisce all’industria alimentare e ai vantaggi speciali che LECO offre a questo mercato.
“Nel campo della tecnologia della scienza della separazione cromatografica, LECO offre GC accoppiato alla spettrometria di massa (MS) del tempo di volo (TOF). Ciò include la cromatografia monodimensionale e bidimensionale (GC×GC), che aumenta la risoluzione e la sensibilità cromatografica. Inoltre, la nostra nuova tecnologia ha un prezzo competitivo rispetto alle alternative a quadrupolo triplo. Inoltre, la tecnologia GC-TOF-MS è praticamente imbattibile nell’analisi dei residui in matrici complesse come tè, spezie, prodotti oleosi, ma anche alimenti per l’infanzia."
eFoodLab // Numero 02/2019 // Intervista a Ralf Löscher
Congratulazioni al vincitore del primo concorso di poster LECO nel Regno Unito, Rachel Hand della De Montfort University/The Open University, e anche alla nostra seconda classificata Sonia García Alcega della The Open University.
Frank Dorman, professore associato di biochimica e biologia molecolare presso la Penn State University, ha parlato al nostro seminario ASMS della sua esperienza con le nostre applicazioni da banco Pegasus BT 4D GC×GC-TOFMS per analizzare la contaminazione ambientale nel fiume Susquehanna.
PEGASUS® GC-HRT+ 4D di LECO sarà la nuova aggiunta alla School of Chemistry della University of Southampton, offrendo capacità uniche ai ricercatori del Regno Unito. Leggi cosa pensa il professor John Langley del nuovo spettrometro di massa. “Lo spettrometro altamente avanzato di Southampton guida la ricerca chimica nella regione meridionale. I ricercatori in tutto il sud dell'Inghilterra analizzeranno composizioni chimiche innovative e strategicamente importante attraverso un nuovo spettrometro di massa presso la University of Southampton.“
Colloqui interessanti, oratori eccellenti, conversazioni e discussioni fantastiche, cibo eccezionale e un luogo straordinario portano a un grande LS3UK a Manchester il 29 e il 30 ottobre.
LECO ti invita a un evento di analisi metabolica diversificato all’EATC di Berlino. Esperti relatori descriveranno come l’uso di LECO GC-TOF-MS e GC×GC-TOF-MS potenzia le loro ultime applicazioni di analisi metabolomica mirata e non mirata in vari campi, ad esempio le malattie umane, la nutrigenomica e i biomarcatori vegetali. Queste lezioni saranno integrate con una sessione di laboratorio che mostrerà la strumentazione e il software LECO più recenti. La partecipazione è gratuita, incluso uno speciale evento serale il 27 novembre!
